40397-96-4
4-chloro-3-nitrophenyl isocyanate
CAS: 40397-96-4
Molecular Formula: C7H3ClN2O3
40397-96-4 - Names and Identifiers
40397-96-4 - Physico-chemical Properties
| Molecular Formula | C7H3ClN2O3 |
| Molar Mass | 198.56 |
| Density | 1.48±0.1 g/cm3(Predicted) |
| Melting Point | 65 °C |
| Boling Point | 306.0±27.0 °C(Predicted) |
| Flash Point | 138.9°C |
| Vapor Presure | 0.000794mmHg at 25°C |
| BRN | 2807129 |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.612 |
40397-96-4 - Risk and Safety
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R42/43 - May cause sensitization by inhalation and skin contact. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. |
| UN IDs | 2811 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
40397-96-4 - Introduction
4-chloro-3-nitrophenyl isocyanate (4-chloro-3-nitrophenyl isocyanate) is an organic compound whose chemical formula is C7H3ClN2O3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-chloroo-3-nitrophenyl isocyanate is white crystal or crystalline powder.
-Solubility: It is soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane at room temperature.
-Melting point: Its melting point is about 95-97°C.
-Stability: It is sensitive to light and heat, and should avoid exposure to sunlight and high temperature environments.
Use:
- 4-chloro-3-nitrophenyl isocyanate is an important organic synthesis intermediate, which has a wide range of uses in the pharmaceutical and pesticide industries.
-It can be used as a raw material for pesticides, such as synthetic pesticides and herbicides.
-In the pharmaceutical industry, it can be used to synthesize some drug precursor compounds.
Preparation Method:
4-chloro-3-nitrophenyl isocyanate can be prepared by reacting isocyanate on 4-chloro-3-nitrobenzene. The specific preparation method can be achieved by a variety of reaction pathways. For example, 4-chloro-3-nitrobenzene can be reacted with an isocyanate in the presence of a chloride under suitable solvent conditions.
Safety Information:
- 4-chloro-3-nitrophenyl isocyanate is a potentially dangerous compound and should be handled with care.
-May cause irritation and injury when in contact with skin, eyes or when inhaling vapors.
-Wear appropriate personal protective equipment such as safety glasses, gloves and protective masks when operating.
-Avoid contact with oxidants and combustibles during handling and storage to avoid the risk of fire and explosion.
-Read and follow the relevant safety technical instructions carefully before use.
Nature:
-Appearance: 4-chloroo-3-nitrophenyl isocyanate is white crystal or crystalline powder.
-Solubility: It is soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane at room temperature.
-Melting point: Its melting point is about 95-97°C.
-Stability: It is sensitive to light and heat, and should avoid exposure to sunlight and high temperature environments.
Use:
- 4-chloro-3-nitrophenyl isocyanate is an important organic synthesis intermediate, which has a wide range of uses in the pharmaceutical and pesticide industries.
-It can be used as a raw material for pesticides, such as synthetic pesticides and herbicides.
-In the pharmaceutical industry, it can be used to synthesize some drug precursor compounds.
Preparation Method:
4-chloro-3-nitrophenyl isocyanate can be prepared by reacting isocyanate on 4-chloro-3-nitrobenzene. The specific preparation method can be achieved by a variety of reaction pathways. For example, 4-chloro-3-nitrobenzene can be reacted with an isocyanate in the presence of a chloride under suitable solvent conditions.
Safety Information:
- 4-chloro-3-nitrophenyl isocyanate is a potentially dangerous compound and should be handled with care.
-May cause irritation and injury when in contact with skin, eyes or when inhaling vapors.
-Wear appropriate personal protective equipment such as safety glasses, gloves and protective masks when operating.
-Avoid contact with oxidants and combustibles during handling and storage to avoid the risk of fire and explosion.
-Read and follow the relevant safety technical instructions carefully before use.
Last Update：2024-04-09 02:00:45
