406933-21-9

406933-21-9 - Names and Identifiers

Name	3-(trifluoromethyl)pyridine-2-carbonitrile
Synonyms	3-Trifluoromethylpicolinonitrile 2-Cyano-3-trifluoromethylpyridine 3-Trifluoromethyl-pyridine-2-carbonitrile 3-(Trifluoromethyl)pyridine-2-carbonitrile 3-(trifluoromethyl)pyridine-2-carbonitrile 2-pyridinecarbonitrile, 3-(trifluoromethyl)- 2-Pyridinecarbonitrile, 3-(trifluoromethyl)- 3-(Trifluoromethyl)-2-picolinonitrile, 2-Cyano-3-(trifluoromethyl)pyridine 3-Trifluoromethyl-2-pyridinecarbonitrile 2-Cyano-3-trifluoromethylpyridine
CAS	406933-21-9
InChI	InChI=1/C7H3F3N2/c8-7(9,10)5-2-1-3-12-6(5)4-11/h1-3H

406933-21-9 - Physico-chemical Properties

Molecular Formula	C7H3F3N2
Molar Mass	172.11
Density	1.37
Boling Point	241℃
Flash Point	99℃
Vapor Presure	0.038mmHg at 25°C
pKa	-2.75±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.457

406933-21-9 - Introduction

3-(trifluoromethyl)pyridine-2-carbonitrile is an organic compound with the chemical formula C7H3F3N2. It is a colorless liquid with a spicy smell.

3-(trifluoromethyl)pyridine-2-carbonitrile is an important intermediate, widely used in organic synthesis. It can be used as a raw material for pharmaceuticals, pesticides and dyes, and can also be used to synthesize other organic compounds, such as compounds containing trifluoromethylpyridine skeleton, pyridine and organic fluorine compounds.

There are two main methods of preparing 3-(trifluoromethyl)pyridine-2-carbonitrile. One is obtained by the reaction of 3-cyanopyridine with trifluoromethyl borate, and the other is obtained by the reaction of 2-picolinate with perfluorinated thiourea followed by hydrolysis.

For its safety information, 3-(trifluoromethyl)pyridine-2-carbonitrile should be considered hazardous. It has an irritating effect on the eyes, skin and respiratory tract. In the process of use, should wear protective gloves, protective glasses and protective masks, maintain good ventilation conditions. During storage and handling, keep away from heat and fire sources and avoid contact with oxidants. In case of contact or inhalation, seek medical attention immediately.

Last Update：2024-04-10 22:29:15