4116-10-3

Name	2-Chloro-N-methylacetoacetamide
Synonyms	4116-10-3 1-Chloroacetoacetomethylamine A-ChloroAcetoN-Methylacetamide N-Methyl-2-chloroacetoacetamide 2-Chloro-N-methylacetoacetamide α-chloro aceto N-methylacetamide 2-chloro-N-methyl-3-oxobutyramide N-Methyl-2-chloro-3-oxobutanamide 2-chloro-N-methyl-3-oxobutanamide 2-chloro-3-keto-N-methyl-butyramide alpha-chloroacetoaceticacidmonoethylamide
CAS	4116-10-3
EINECS	223-907-5
InChI	InChI=1/C5H8ClNO2/c1-3(8)4(6)5(9)7-2/h4H,1-2H3,(H,7,9)

Molecular Formula	C5H8ClNO2
Molar Mass	149.58
Density	1.2253 (rough estimate)
Melting Point	78-80°C
Boling Point	284.1±30.0 °C(Predicted)
Flash Point	125.6°C
Vapor Presure	0.00304mmHg at 25°C
pKa	10.01±0.46(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.5500 (estimate)
Physical and Chemical Properties	The product is crystalline, m. P. 79.2~80 °c.

Hazard Symbols	T - Toxic
Risk Codes	R22 - Harmful if swallowed R24 - Toxic in contact with skin R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	2923
RTECS	AK3910000
Hazard Class	8
Packing Group	III

EPA chemical information	Information provided by: ofmpub.epa.gov (external link)
use	α-acetylmethamine chloride is a special intermediate for the insecticide monocrotophos.
Production method	The preparation method is obtained by chlorination of acetylmethamine. Put acetylethylamine aqueous solution into the enamel reaction kettle, add urine brine made of salt and urea, add a small amount of dichloroethane, stir and cool to below -15 ℃, then slowly pass in chlorine gas, take samples and analyze according to a certain amount, then pump into the extraction kettle, heat to 40 ℃, extract with dichloroethane, extract the extract into the concentration kettle, and evaporate dichloroethane under normal pressure to obtain α-chloroacetylethylamine, you can directly enter the synthesis kettle for the next reaction.
category	toxic substances
toxicity classification	poisoning
acute toxicity	oral-rat LD50: 700 mg/kg; Oral-mouse LD50: 750 mg/kg
flammability hazard characteristics	thermal decomposition of toxic nitrogen oxides, chloride gas
storage and transportation characteristics	warehouse ventilation and low temperature drying
fire extinguishing agent	carbon dioxide, water, foam, dry powder