41451-75-6 - Names and Identifiers
Name | Bruceantin
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Synonyms | Bruceantin NCI 165563 NSC 165563 Crow gall Pavilion Bruceantin(NSC165563) Yadanziyou Oleum Bruceae 2H-3,11c-(Epoxymethano)phenanthro[10,1-bc]pyran, picras-3-en-21-oic acid deriv. Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)-
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CAS | 41451-75-6
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41451-75-6 - Physico-chemical Properties
Molecular Formula | C28H36O11
|
Molar Mass | 548.58 |
Density | 1.2262 (rough estimate) |
Melting Point | 225-226℃ |
Boling Point | 540.78°C (rough estimate) |
Specific Rotation(α) | D25 -43° (c = 0.31 in pyridine) |
Solubility | Soluble in methanol, ethanol, chloroform, ether and other organic solvents. |
Appearance | Solid |
Color | White to Off-White |
pKa | 8.81±0.70(Predicted) |
Storage Condition | -20°C Freezer |
Refractive Index | 1.5970 (estimate) |
MDL | MFCD00866510 |
Physical and Chemical Properties | Crow gall pavilion is a white crystalline powder, insoluble in water, soluble in methanol, ethanol, chloroform, ether and other organic solvents. |
Use | Crow gall pavilion is a plant of bitter wood family anti-dysentery Brucea javanica antidysenterica Mill. Brucea javanica B javacina (l.)Merr. Seeds can be used for content determination, identification, pharmacological experiments, etc. |
41451-75-6 - Risk and Safety
Toxicity | LD50 in male, female mice (mg/kg): 1.95, 2.58 i.v. (Castles) |
41451-75-6 - Introduction
Open Data Unverified Data
Bioactive Bruceantin(NSC165563), which can be extracted from Brucea javanica dysentery, is inhibitory to B16 melanoma, colon cancer 38,L1210 and leukemia P388.
Category Toxic
Last Update:2024-04-09 19:43:38
41451-75-6 - Reference Information
Open Data Unverified Data
properties | crow gall pavilion is a white crystalline powder, insoluble in water, soluble in methanol, ethanol, chloroform, ether and other organic solvents. |
apply | crow gall pavilion as anti-dysentery Brucea brucea antidysenterica Mill. Brucea brucea B javacina(L.)Merr. Seeds can be used for content determination, identification, pharmacological experiments, etc. |
biological activity | Bruceantin(NSC165563) can be extracted from javanica javanica and has inhibitory effect on B16 melanoma, colon cancer 38,L1210 and leukemia P388. |
category | toxic substances |
Last Update:2024-04-09 19:43:38