41748-71-4 - Names and Identifiers
41748-71-4 - Physico-chemical Properties
Molecular Formula | C7H7N3
|
Molar Mass | 133.15 |
Density | 1.367±0.06 g/cm3(Predicted) |
Melting Point | 148-150°C |
Boling Point | 376.6±15.0 °C(Predicted) |
Flash Point | 209.5°C |
Vapor Presure | 7.16E-06mmHg at 25°C |
pKa | 15.61±0.40(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.78 |
41748-71-4 - Risk and Safety
Hazard Symbols | Xn - Harmful

|
Risk Codes | R34 - Causes burns
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S22 - Do not breathe dust.
|
UN IDs | 3259 |
HS Code | 29339900 |
Hazard Class | IRRITANT |
41748-71-4 - Introduction
1H-indazol-4-amine is an organic compound with the chemical formula C7H7N3. It is an indole derivative with one amino substituent on the indole ring. The following is a description of the nature, use, preparation and safety information of 1H-indazol-4-amine:
Nature:
-Appearance: 1H-indazol-4-amine is a white to pale yellow solid.
-Melting point: Its melting point is 119-121 degrees Celsius.
-Solubility: 1H-indazol-4-amine is almost insoluble in water, but can be dissolved in some organic solvents, such as ethanol and dimethylformamide.
-Chemical properties: It is a weak base and can participate in some organic reactions, such as electrophilic substitution reactions and coupling reactions.
Use:
- 1H-indazol-4-amine is an important intermediate compound used in the synthesis of various organic compounds and drugs.
-It is widely used in the field of medicine and can be used to synthesize biologically active compounds and used as raw materials for drugs.
-Because 1H-indazol-4-amine has a good anti-tumor effect, it is also studied and used to develop anti-cancer drugs.
Preparation Method:
- 1H-indazol-4-amine can be synthesized by several methods. One of the common methods is to react indole and ammonia in a suitable solvent to obtain the product.
-The preparation process may involve some organic synthesis reagents and conditions, and the specific synthesis method needs to be selected according to specific needs.
Safety Information:
- 1H-indazol-4-amine is generally considered to be relatively safe under routine use. However, any chemical should be handled and stored under appropriate conditions and in accordance with relevant safety guidelines.
-It may cause irritation to the eyes, skin, and respiratory tract, so proper safety measures, such as wearing protective glasses, gloves, and respiratory protection, are required for use.
-If you accidentally ingest or come into contact with 1H-indazol-4-amine, you should immediately rinse the affected area with water and seek medical help as needed.
Last Update:2024-04-09 20:49:11