41941-56-4
8-Chloroadenosine-3',5'-O-monophosphate
CAS: 41941-56-4
Molecular Formula: C10H11ClN5O6P
41941-56-4 - Names and Identifiers
| Name | 8-Chloroadenosine-3',5'-O-monophosphate |
| Synonyms | 8-CL-CAMP 8-CHLORO-CAMP 8-Chloroadenosine-3',5'-O-monophosphate 8-Chloroadenosine 3',5'-phosphoric acid 8-Chloro cyclic adenosine 3',5'-phosphate 8-CHLOROADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE 8-CHLOROADENOSINE-CYCLIC-3',5'-MONOPHOSPHATE 8-Chloroadenosine 3',5'-Cyclicmonophate Sodium Salt 8-Chloro-cAMP, 8-Chloroadenosine 3μ,5μ-monophosphate, 8-Cl-cAMP |
| CAS | 41941-56-4 |
| InChI | InChI=1/C10H11ClN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14) |
41941-56-4 - Physico-chemical Properties
| Molecular Formula | C10H11ClN5O6P |
| Molar Mass | 363.65 |
| Density | 2.55±0.1 g/cm3(Predicted) |
| Boling Point | 731.7±70.0 °C(Predicted) |
| Flash Point | 396.3°C |
| Solubility | aqueous base: soluble |
| Vapor Presure | 1.77E-22mmHg at 25°C |
| Appearance | White to off-white powder. |
| pKa | 0.95±0.60(Predicted) |
| Storage Condition | −20°C |
| Refractive Index | 2.009 |
41941-56-4 - Risk and Safety
| WGK Germany | 3 |
| RTECS | AU7357552 |
41941-56-4 - Introduction
8-Chloroadenosine-3 ',5'-O-monophosphate is an organic compound in the form of the sodium salt of 8-chloroadenosine and 3 ',5'-cyclic phosphate. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White solid
-Solubility: Soluble in water and inorganic salt solution
-Stability: relatively stable, but may degrade under light conditions
- pH: generally stable under neutral or weakly acidic conditions
Use:
8-Chloroadenosine-3 ',5'-O-monophosphate has important applications in biochemistry and cell biology. It is often used as an activator to promote the adenylate cyclization reaction in cells. In addition, it can also be used to study related signal transduction pathways and cell signaling mechanisms, such as cAMP signaling pathway.
Preparation Method:
8-Chloroadenosine-3 ',5'-O-monophosphate can be obtained by reacting 8-chloroadenosine with dimethyl trimethylphosphonate (DMPA) and then trimethylphosphonate (TMPA). Finally, the sodium salt form is obtained by reaction with triethylamine and phosphorus oxychloride.
Safety Information:
Limited safety information regarding 8-Chloroadenosine-3 ',5'-O-monophosphate is currently available. Personal protective measures such as wearing protective gloves and goggles should be taken during handling and handling. In addition, the storage and handling of compounds should follow proper laboratory safe operating procedures. It needs to be used in a specialized laboratory environment and in compliance with local chemical regulations. If ingestion or contact with eyes or skin, seek medical attention immediately.
Nature:
-Appearance: White solid
-Solubility: Soluble in water and inorganic salt solution
-Stability: relatively stable, but may degrade under light conditions
- pH: generally stable under neutral or weakly acidic conditions
Use:
8-Chloroadenosine-3 ',5'-O-monophosphate has important applications in biochemistry and cell biology. It is often used as an activator to promote the adenylate cyclization reaction in cells. In addition, it can also be used to study related signal transduction pathways and cell signaling mechanisms, such as cAMP signaling pathway.
Preparation Method:
8-Chloroadenosine-3 ',5'-O-monophosphate can be obtained by reacting 8-chloroadenosine with dimethyl trimethylphosphonate (DMPA) and then trimethylphosphonate (TMPA). Finally, the sodium salt form is obtained by reaction with triethylamine and phosphorus oxychloride.
Safety Information:
Limited safety information regarding 8-Chloroadenosine-3 ',5'-O-monophosphate is currently available. Personal protective measures such as wearing protective gloves and goggles should be taken during handling and handling. In addition, the storage and handling of compounds should follow proper laboratory safe operating procedures. It needs to be used in a specialized laboratory environment and in compliance with local chemical regulations. If ingestion or contact with eyes or skin, seek medical attention immediately.
Last Update：2024-04-09 21:54:55
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