4226-01-1
Tributyltinlithium
CAS: 4226-01-1
Molecular Formula:
4226-01-1 - Names and Identifiers
| Name | Tributyltinlithium |
| Synonyms | Tributyltinlithium Lithium tributyltin Tri-n-butyltin lithium Tributyllithiostannane (Tributylstannyl)lithium Lithium tributylstannate |
| CAS | 4226-01-1 |
4226-01-1 - Physico-chemical Properties
| Molar Mass | 296.99 |
4226-01-1 - Reference Information
| introduction | tributyltin lithium is an important metal tin reagent in modern organic synthesis. it can be prepared in situ very conveniently and can undergo nucleophilic reactions with aldehydes, ketones, halogenated hydrocarbons, sulfonic acid esters and α,β-unsaturated esters. |
| Application | Under normal circumstances, tributyltin lithium can be regarded as an alkyl lithium reagent as a whole. It undergoes a nucleophilic addition reaction with aldehydes and ketones to produce α-hydroxytributyltin. Tributyltin lithium is also a very ideal Michael addition donor, which can undergo normal Michael addition reaction with α,β-unsaturated esters. |
| Preparation | Usually prepared in situ before the reaction: at -78°C, add n-butyl lithium solution dropwise to the THF solution of tributyltin hydrogen to obtain tributyltin lithium, which can be directly used in subsequent reactions without separation and purification. |
Last Update：2024-04-09 21:04:16
