42580-42-7

42580-42-7 - Names and Identifiers

Name	2,5-bis(trifluoromethyl)benzoic acid
Synonyms	RARECHEM AL BO 1002 2,5-DI(TRIFLUOROMETHYL)BENZOIC ACID 2,5-BIS(TRIFLUOROMETHYL)BENZOIC ACID 2,5-Bis(trifluoromethyl)benzoic acid 2,5-bis(trifluoromethyl)benzoic acid 2,5-Bis(Trifluoromethoxy)Benzoic Acid Benzoic acid, 2,5-bis(trifluoromethyl)- 2-chloro-1,1,2-trifluoro-1-methoxyethane
CAS	42580-42-7
EINECS	207-038-9
InChI	InChI=1/C9H4F6O2/c10-8(11,12)4-1-2-6(9(13,14)15)5(3-4)7(16)17/h1-3H,(H,16,17)

42580-42-7 - Physico-chemical Properties

Molecular Formula	C9H4F6O2
Molar Mass	258.12
Density	1.527±0.06 g/cm3(Predicted)
Melting Point	78-80°C(lit.)
Boling Point	248.5±40.0 °C(Predicted)
Flash Point	104.1°C
Vapor Presure	0.0128mmHg at 25°C
pKa	2.80±0.36(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.424
MDL	MFCD00013249

42580-42-7 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29163990
Hazard Class	IRRITANT

42580-42-7 - Introduction

2,5-bis(trifluoromethyl)benzoic acid is an organic compound with the chemical formula C9H4F6O2. The following is a description of its nature, use, preparation and safety information:

Nature:
- 2,5-bis(trifluoromethyl)benzoic acid is a colorless to pale yellow crystalline or powdery solid.
-Almost insoluble in water at room temperature, but soluble in organic solvents such as ether and dichloromethane.
-It has a strong corrosive and pungent odor.

Use:
- 2,5-bis(trifluoromethyl)benzoic acid is a commonly used reagent in organic synthesis, which can be used to synthesize compounds such as drugs, dyes and materials.
-It can be used as a catalyst for organic synthesis reactions, such as aromatization reactions and carboxylation reactions.
-In addition, it is also used for the preparation of electronic materials and the surface modification of optical materials.

Preparation Method:
- 2,5-bis(trifluoromethyl)benzoic acid can be synthesized by reacting 2,5-difluoromethylbenzoic acid with a trifluoromethylating reagent (such as trifluoromethyl chloride).
-This reaction is generally carried out under an inert atmosphere and uses a catalyst under acidic or basic conditions.

Safety Information:
- 2,5-bis(trifluoromethyl)benzoic acid is highly corrosive and can cause severe irritation and damage when in contact with skin and eyes.
-Wear appropriate protective equipment such as gloves, goggles and protective clothing during operation.
-This compound should be kept away from fire and oxidizing agents, and placed in a sealed container to prevent contact with air and water.
-Proper chemical laboratory safety practices must be followed during use and storage.

Last Update：2024-04-09 20:52:54