42607-87-4
THP-PEG6-OH
CAS: 42607-87-4
Molecular Formula: C17H34O8
42607-87-4 - Names and Identifiers
| Name | THP-PEG6-OH |
| Synonyms | THP-PEG7 OH-PEG6-THP THP-PEG6-OH THP-PEG6-alcohol 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-[(tetrahydro-2H-pyran-2-yl)oxy]- |
| CAS | 42607-87-4 |
42607-87-4 - Physico-chemical Properties
| Molecular Formula | C17H34O8 |
| Molar Mass | 366.45 |
| Density | 1.10±0.1 g/cm3(Predicted) |
| Boling Point | 469.0±45.0 °C(Predicted) |
| pKa | 14.36±0.10(Predicted) |
| Storage Condition | 2-8°C，干燥，密封 |
| MDL | MFCD26793752 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
42607-87-4 - Reference Information
| biological activity | THP-PEG6-OH is a PROTAC linker belonging to the PEG class. THP-PEG6-OH can be used for the synthesis of PROTAC molecules. THP-PEG6-OH is also a non-cleavable ADC linker containing 6 units of PEG, which can be used to synthesize antibody conjugated drugs (ADC). |
Last Update：2024-04-09 20:52:54
