431888-57-2
2-Chloro-4-(methoxycarbonyl)benzoic acid
CAS: 431888-57-2
Molecular Formula: C9H7ClO4
431888-57-2 - Names and Identifiers
431888-57-2 - Physico-chemical Properties
| Molecular Formula | C9H7ClO4 |
| Molar Mass | 214.6 |
| Density | 1.413±0.06 g/cm3(Predicted) |
| Boling Point | 360.3±27.0 °C(Predicted) |
| pKa | 2.43±0.25(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD21603679 |
431888-57-2 - Introduction
2-Chloro-4-(methoxycarbonyl)benzoic acid is an organic compound whose chemical formula is C9H7ClO4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Chloro-4-(methoxycarbonyl)benzoic acid is a white crystalline solid.
-Melting point: about 147-149°C.
-Soluble: It is soluble in common organic solvents such as methanol, ethanol and dichloromethane.
Use:
-Chemical synthesis: 2-Chloro-4-(methoxycarbonyl)benzoic acid can be used as raw materials and intermediates in organic synthesis.
-Pharmaceutical field: The compound also has some applications in pharmaceutical research.
Preparation Method:
- 2-Chloro-4-(methoxycarbonyl)benzoic acid can be prepared by a variety of methods. A common method is obtained by reacting 2-chloro-4-carboxybenzoic anhydride with methoxy lithium in the presence of sodium chloride. After completion of the reaction, the product is extracted from the reaction mixture by acidification and crystallized in a suitable solvent to obtain the desired product.
Safety Information:
2-Chloro-4-(methoxycarbonyl)benzoic acid may cause irritation to the skin, eyes and respiratory system under normal operating conditions.
-During operation, appropriate personal protective equipment should be selected, such as chemical goggles, protective gloves and protective masks.
-When using or handling this compound, correct laboratory operating instructions and disposal procedures must be followed.
-During storage and transportation, it should be stored in a dry, cool, and well-ventilated place.
Nature:
-Appearance: 2-Chloro-4-(methoxycarbonyl)benzoic acid is a white crystalline solid.
-Melting point: about 147-149°C.
-Soluble: It is soluble in common organic solvents such as methanol, ethanol and dichloromethane.
Use:
-Chemical synthesis: 2-Chloro-4-(methoxycarbonyl)benzoic acid can be used as raw materials and intermediates in organic synthesis.
-Pharmaceutical field: The compound also has some applications in pharmaceutical research.
Preparation Method:
- 2-Chloro-4-(methoxycarbonyl)benzoic acid can be prepared by a variety of methods. A common method is obtained by reacting 2-chloro-4-carboxybenzoic anhydride with methoxy lithium in the presence of sodium chloride. After completion of the reaction, the product is extracted from the reaction mixture by acidification and crystallized in a suitable solvent to obtain the desired product.
Safety Information:
2-Chloro-4-(methoxycarbonyl)benzoic acid may cause irritation to the skin, eyes and respiratory system under normal operating conditions.
-During operation, appropriate personal protective equipment should be selected, such as chemical goggles, protective gloves and protective masks.
-When using or handling this compound, correct laboratory operating instructions and disposal procedures must be followed.
-During storage and transportation, it should be stored in a dry, cool, and well-ventilated place.
Last Update：2024-04-09 02:00:56
