437982-59-7
tert-butyl 5-amino-3-cyclopropyl-1H-pyrazole-1-carboxylate
CAS: 437982-59-7
Molecular Formula: C11H17N3O2
437982-59-7 - Names and Identifiers
| Name | tert-butyl 5-amino-3-cyclopropyl-1H-pyrazole-1-carboxylate |
| Synonyms | tert-butyl 5-amino-3-cyclopropyl-1H-pyrazole-1-carboxylate |
| CAS | 437982-59-7 |
437982-59-7 - Physico-chemical Properties
| Molecular Formula | C11H17N3O2 |
| Molar Mass | 223.27 |
437982-59-7 - Introduction
tert-butyl is an organic compound with the chemical formula C13H18N4O4. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 120-123°C
-Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide (DMF) and dichloromethane
-Stability: relatively stable under normal storage conditions
Use:
- tert-butyl can be used as synthetic drug intermediates, such as for the synthesis of antibacterial drugs or pesticides
-It can also be used as a reagent in organic synthesis reactions
Preparation Method:
- tert-butyl preparation can be completed by reaction sequence: first, tert-butyl carbamate and bromoacetate are condensed with pyridine as catalyst to obtain tert-butyl 3-(tert-butoxycarbonyl)amino-3-(bromomethyl)cyclopropane-1-carboxylate; Then, the above intermediate is reacted with 5-nitro-yamin with heterocyclic compound 1,2-diphenylethylenediamine as catalyst, the final product is generated.
Safety Information:
- tert-butyl is a chemical that is irritating and corrosive to the skin and eyes. Wear appropriate personal protective equipment such as gloves and goggles when using it.
-During operation, avoid inhaling its gas or swallowing its solid form.
-Please store it in a dry place away from light, low temperature, and away from combustibles and oxidants.
-When handling the compound, follow the correct laboratory operating procedures and comply with the relevant regulations and regulations on chemicals.
Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 120-123°C
-Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide (DMF) and dichloromethane
-Stability: relatively stable under normal storage conditions
Use:
- tert-butyl can be used as synthetic drug intermediates, such as for the synthesis of antibacterial drugs or pesticides
-It can also be used as a reagent in organic synthesis reactions
Preparation Method:
- tert-butyl preparation can be completed by reaction sequence: first, tert-butyl carbamate and bromoacetate are condensed with pyridine as catalyst to obtain tert-butyl 3-(tert-butoxycarbonyl)amino-3-(bromomethyl)cyclopropane-1-carboxylate; Then, the above intermediate is reacted with 5-nitro-yamin with heterocyclic compound 1,2-diphenylethylenediamine as catalyst, the final product is generated.
Safety Information:
- tert-butyl is a chemical that is irritating and corrosive to the skin and eyes. Wear appropriate personal protective equipment such as gloves and goggles when using it.
-During operation, avoid inhaling its gas or swallowing its solid form.
-Please store it in a dry place away from light, low temperature, and away from combustibles and oxidants.
-When handling the compound, follow the correct laboratory operating procedures and comply with the relevant regulations and regulations on chemicals.
Last Update：2024-04-09 21:01:54
