446-09-3

446-09-3 - Names and Identifiers

Name	2-Bromo-5-fluoronitrobenzene
Synonyms	2-Bromo-5-fluoronitrobenzene 2-BROMO-5-FLUORONITROBENZENE 2-Bromo-5-fluoroanitrobenzene 1-BroMo-4-Fluoro-2-nitrobenzebe 1-Bromo-4-fluoro-2-nitrobenzene 1-Bromo-2-nitro-4-fluorobenzene 1-BROMO-4-FLUORO-2-NITROBENZENE
CAS	446-09-3
EINECS	207-160-2
InChI	InChI=1/C6H3BrFNO2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H
InChIKey	XRXNWKIKQFEOGO-UHFFFAOYSA-N

446-09-3 - Physico-chemical Properties

Molecular Formula	C6H3BrFNO2
Molar Mass	220
Density	1.808±0.06 g/cm3(Predicted)
Melting Point	37-39°C
Boling Point	148-150°C 35mm
Flash Point	148-150°C/35mm
Vapor Presure	0.164mmHg at 25°C
Appearance	Crystallization
Color	White or Colorless to Yellow to Green
BRN	2364227
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.579
MDL	MFCD00055530

446-09-3 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves.
UN IDs	UN2811
HS Code	29049090
Hazard Note	Irritant
Hazard Class	6.1
Packing Group	III

446-09-3 - Introduction

2-Bromo-5-fluorontrobenzene is an organic compound with the chemical formula C6H3BrFNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2-Bromo-5-fluorontrobenzene is a colorless or slightly yellow crystalline solid.
-Melting point: about 48-52°C.
-Boiling point: about 283°C.
-Density: about 1.8g/cm³.
-Solubility: It has good solubility in common organic solvents such as ethanol, methanol and dichloromethane.

Use:
- 2-Bromo-5-fluoronitrobenzene is commonly used as an intermediate in organic synthesis and is widely used in the fields of drug synthesis, dye synthesis and pesticide synthesis.
-It can also be used as a research compound to study organic reaction mechanism and catalyst activity.

Preparation Method:
- 2-Bromo-5-fluoronitrobenzene can be prepared by reacting 2-Bromo-5-fluoronitrobenzene phenol with sodium nitrite under acidic conditions.

Safety Information:
- 2-Bromo-5-fluoronitrobenzene is an organic compound and requires attention to safe operation.
-The substance has a certain acute toxicity, may cause irritation, corrosion or other adverse effects on the human body.
-Wear appropriate personal protective equipment when using or handling the compound, including chemical protective gloves, goggles, and protective masks.
-During storage and handling, avoid contact with oxidants, organic alkalis and combustibles to avoid dangerous chemical reactions and explosions.
-When discarded, it should be disposed of in accordance with local regulations to avoid pollution to the environment.

Last Update：2024-04-09 19:05:49