44864-47-3
(2R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid
CAS: 44864-47-3
Molecular Formula: C4H5F3O3
44864-47-3 - Names and Identifiers
44864-47-3 - Physico-chemical Properties
| Molecular Formula | C4H5F3O3 |
| Molar Mass | 158.08 |
| Density | 1.532±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 110 °C |
| Boling Point | 247.4±35.0℃ (760 Torr) |
| Flash Point | 103.4±25.9℃ |
| Water Solubility | Soluble in water |
| Vapor Presure | 0.0042mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| pKa | 2.46±0.22(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 16.5 ° (C=5, H2O) |
| MDL | MFCD03095400 |
44864-47-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S24/25 - Avoid contact with skin and eyes. |
| UN IDs | 3261 |
| HS Code | 29155090 |
| Hazard Class | IRRITANT |
| Packing Group | III |
44864-47-3 - Introduction
(R)-3,3, 3-Trifluoro-2-hydroxy-2-methylpropionic acid is an organic compound with the chemical formula C4H7F3O3.
Nature:
-Appearance: Colorless liquid or white solid.
-Melting point: about 50°C.
-Boiling point: about 200°C.
-Solubility: Soluble in water, alcohol and ether.
Use:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid is often used as a chiral building block in drug synthesis, and can be used to synthesize chiral drugs and pesticides.
-It can also be used to synthesize regular optical molecules and potential materials applications.
Preparation Method:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid can be synthesized by fluorination reaction.
-The specific synthesis method may be to react 2-methylmalonic acid with hydrofluoric acid under appropriate conditions to obtain (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid.
Safety Information:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid is an organic acid, which is relatively stable and generally does not have serious toxicity and irritation.
-During use and handling, direct contact with skin and eyes should be avoided, inhalation or intake should be avoided, and good ventilation conditions should be maintained.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing during use.
-When handling waste, it should be handled and disposed in accordance with relevant laws and regulations.
Nature:
-Appearance: Colorless liquid or white solid.
-Melting point: about 50°C.
-Boiling point: about 200°C.
-Solubility: Soluble in water, alcohol and ether.
Use:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid is often used as a chiral building block in drug synthesis, and can be used to synthesize chiral drugs and pesticides.
-It can also be used to synthesize regular optical molecules and potential materials applications.
Preparation Method:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid can be synthesized by fluorination reaction.
-The specific synthesis method may be to react 2-methylmalonic acid with hydrofluoric acid under appropriate conditions to obtain (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid.
Safety Information:
- (R)-3,3, 3-trifluoro-2-hydroxy-2-methylpropionic acid is an organic acid, which is relatively stable and generally does not have serious toxicity and irritation.
-During use and handling, direct contact with skin and eyes should be avoided, inhalation or intake should be avoided, and good ventilation conditions should be maintained.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing during use.
-When handling waste, it should be handled and disposed in accordance with relevant laws and regulations.
Last Update：2024-04-09 02:00:46
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Spot supply
Product Name: (R)-2-Hydroxy-2-(Trifluoromethyl)Propionic Acid Visit Supplier Webpage Request for quotationCAS: 44864-47-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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