448944-56-7
methyl 3-[tert-butyl(dimethyl)silyl]oxypropanoate
CAS: 448944-56-7
Molecular Formula: C10H22O3Si
448944-56-7 - Names and Identifiers
448944-56-7 - Physico-chemical Properties
| Molecular Formula | C10H22O3Si |
| Molar Mass | 218.37 |
448944-56-7 - Upstream Downstream Industry
| Downstream Products | 3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL |
448944-56-7 - Introduction
methyl 3-[tert-butyl] oxypropanoate is an organic compound. Its chemical formula is C10H22O4Si and its molecular weight is 226.36g/mol.
methyl 3-[tert-butyl(dimethyl)silyl] oxypanoate is a transparent liquid, soluble in organic solvents at room temperature. It is an ester compound containing one hydroxyl group and one methyl ester group. In addition, it contains one tert-t-butyl and two dimethylsilyl substituents. These substituents provide the compound with high thermal stability and hydrolysis resistance.
methyl 3-[tert-butyl(dimethyl)silyl] oxypanoate is widely used in organic synthesis reactions as a protecting group or reagent. It can protect the hydroxyl group by introducing tert-butyl and dimethylsilyl groups on the hydroxyl group to prevent accidental chemical reactions in the reaction. In chemical synthesis, methyl 3-[tert-butyl] oxypanoate is often used as a hydroxyl protecting reagent to remove protecting groups when needed.
methyl 3-[tert-butyl] oxypropanoate is prepared by reacting methyl 3-hydroxypropionate with tert-butyl copper iodide and trimethylsilyl chloride. After the reaction, the product is isolated and purified by distillation or crystallization.
When using methyl 3-[tert-butyl (dimer) silyl] oxypropylanoate, you need to pay attention to its safety. It is a flammable liquid and should avoid contact with fire sources. It is recommended to wear appropriate protective gloves and glasses to protect the skin and eyes when handling. At the same time, it should be operated in a well-ventilated place to avoid inhaling steam or generating steam. Use should be stored in a sealed container, away from fire and oxidizing agents.
methyl 3-[tert-butyl(dimethyl)silyl] oxypanoate is a transparent liquid, soluble in organic solvents at room temperature. It is an ester compound containing one hydroxyl group and one methyl ester group. In addition, it contains one tert-t-butyl and two dimethylsilyl substituents. These substituents provide the compound with high thermal stability and hydrolysis resistance.
methyl 3-[tert-butyl(dimethyl)silyl] oxypanoate is widely used in organic synthesis reactions as a protecting group or reagent. It can protect the hydroxyl group by introducing tert-butyl and dimethylsilyl groups on the hydroxyl group to prevent accidental chemical reactions in the reaction. In chemical synthesis, methyl 3-[tert-butyl] oxypanoate is often used as a hydroxyl protecting reagent to remove protecting groups when needed.
methyl 3-[tert-butyl] oxypropanoate is prepared by reacting methyl 3-hydroxypropionate with tert-butyl copper iodide and trimethylsilyl chloride. After the reaction, the product is isolated and purified by distillation or crystallization.
When using methyl 3-[tert-butyl (dimer) silyl] oxypropylanoate, you need to pay attention to its safety. It is a flammable liquid and should avoid contact with fire sources. It is recommended to wear appropriate protective gloves and glasses to protect the skin and eyes when handling. At the same time, it should be operated in a well-ventilated place to avoid inhaling steam or generating steam. Use should be stored in a sealed container, away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
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