Name | acedapsone |
Synonyms | 1399 f Camilan acedapsone 44SULPHONYLBISACETANILIDE 4',4'''-sulfonylbis-acetanilid 4',4'''-sulfonylbis(acetanilide) 4,4'-diacetamidodiphenyl sulfone 4,4'-diacetylaminodiphenyl sulfone 4,4'-diacetyldiaminodiphenyl sulfone |
CAS | 77-46-3 |
EINECS | 2010288 |
Molecular Formula | C16H16N2O4S |
Molar Mass | 332.378 |
Density | 1.2982 (rough estimate) |
Melting Point | 289-292° |
Refractive Index | 1.6930 (estimate) |
Physical and Chemical Properties | White or yellowish crystals, odorless. Almost insoluble in water. Melting point 289~292 ℃. |
use | anti-leprosy drugs. |
Production method | It is obtained by heating and refluxing dapsone, acetic acid and acetic anhydride, and acetylation. The obtained crude product is decolorized and refined with activated carbon in ethanol to obtain the fine products of acetamide phenyl sulfone. For dapsone, the total yield is about 76%. |