453-11-2
1-CHLORO-3-FLUOROISOPROPANOL
CAS: 453-11-2
Molecular Formula: C3H6ClFO
453-11-2 - Names and Identifiers
453-11-2 - Physico-chemical Properties
| Molecular Formula | C3H6ClFO |
| Molar Mass | 112.53 |
| Density | 1.3 |
| Boling Point | 153 °C |
| Flash Point | 153-156°C |
| BRN | 1732501 |
| pKa | 12.77±0.20(Predicted) |
| Refractive Index | 1.438 |
| Physical and Chemical Properties | Colorless or yellowish transparent liquid with slightly sour taste. B. p.120 ~ 130 ℃, relative density 1.25~1.27 (23 ℃), of which compound a accounts for 70%, B. p. 127~128 ℃, relative density 1.244 (20 ℃), refractive index 1.3800 (20 ℃); Compound B accounts for 30%, B. p. is 146~148 ℃, relative density is 1.300 (20 ℃), and refractive index is 1.4360 (20 ℃). It can be dissolved in water, ethanol, ether and other organic solvents. It has stable chemical properties in acidic solution, can be decomposed in alkaline solution, and is volatile and toxic at high temperature. |
453-11-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R10 - Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S23 - Do not breathe vapour. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 2929 |
| Hazard Note | Irritant |
| Hazard Class | 3 |
| Packing Group | III |
453-11-2 - References
| toxicity | Acute oral LD50 for brown rabbits was 30.0mg/kg(LD5035mg/kg ), 3.38mg/kg for Davil, 4.5mg/kg for citellus chinensis, 10.0mg/kg for gerbil, 2.8mg/kg for Chinese gerbil and 4.0mg/kg for guinea pig. It is safer for poultry, LD501500mg/kg for chicken and 2000mg/kg for duck. High toxicity to livestock. Ames test, mouse bone marrow cell micronucleus test, mouse testis original cell chromosome aberration test were negative, no obvious accumulation. |
| Use | a highly toxic, rapid-acting fluoroalcohol rodenticide. It is mainly used for rodent control in the field, especially in grassland and pastoral areas. Can be absorbed through the skin, can be the digestive system, respiratory system or skin contact caused by rat poisoning death. When using the content of 0.6, for residential, warehouse, ship and other rodent control, put the bait into the rat hole (next to) or the places where the rats often move, put 4 piles in each room, 5~10G for each pile, 10G for each hole in the field, dead rats were found 24h after administration, and the peak appeared 2 ~ 4d, and the rodent infestation was controlled after 4d. |
| production method | a mixture of epichlorohydrin and hydrogen fluoride-potassium fluoride was refluxed by heating at 118 °c with diethylene glycol as the solvent. After the reaction, the mouse was distilled under reduced pressure to obtain the mouse. Alternatively, the reaction of Epichlorohydrin with KHF2 in diethylene glycol at 160-170 ° C. Is carried out under reduced pressure and by atmospheric distillation to obtain a rat Valerian. |
| category | pesticide |
| toxicity grade | high toxicity |
| Acute toxicity | intravenous injection-mouse LD50: 320 mg/kg |
| flammability hazard characteristics | thermal decomposition of toxic halide gases |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
| fire extinguishing agent | Sand, dry powder, foam |
Last Update：2024-04-09 20:52:54
