45438-80-0
2-Thienylzinc bromide
CAS: 45438-80-0
Molecular Formula: C4H3BrSZn
45438-80-0 - Names and Identifiers
45438-80-0 - Physico-chemical Properties
| Molecular Formula | C4H3BrSZn |
| Molar Mass | 228.43 |
| Density | 0.973g/mLat 25°C |
| Flash Point | 1°F |
| Water Solubility | Reacts with water. |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
45438-80-0 - Risk and Safety
| Risk Codes | R11 - Highly Flammable R19 - May form explosive peroxides R36/37 - Irritating to eyes and respiratory system. R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S16 - Keep away from sources of ignition. S29 - Do not empty into drains. S33 - Take precautionary measures against static discharges. S36/37 - Wear suitable protective clothing and gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 3399 4.3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29319090 |
| Hazard Class | 4.3 |
45438-80-0 - Introduction
2-Thienylzinc bromide is an organic compound with the chemical formula C4H3BrS Zn. The following is a description of the nature, use, preparation and safety information of 2-Thienylzinc bromide:
Nature:
-Appearance: 2-Thienylzinc bromide is a white to pale yellow solid.
-Solubility: Can be dissolved in organic solvents such as ether and dichloromethane.
-Stability: It is air-sensitive, so it needs to be treated under inert gas.
Use:
-Synthesis: 2-Thienylzinc bromide is an important reagent in organic synthesis. It can be used to synthesize other organic molecules, such as organometallic compounds or compounds containing thiophene groups.
-Catalyst: 2-Thienylzinc bromide is also used as a catalyst for cross-coupling reactions, such as the Tokner metal addition reaction.
Preparation Method:
- 2-Thienylzinc bromide can be prepared by reacting thiophene with ethyl zinc bromide. The thiophene was first reacted with copper iodide and then with ethylzinc bromide under an inert atmosphere to give finally 2-Thienylzinc bromide.
Safety Information:
Dust and vapours from the-2-Thienylzinc bromide may cause irritation and damage to the eyes, skin and respiratory system. Care should therefore be taken to avoid contact and inhalation.
-Wear appropriate protective gloves, goggles and protective mask during use and handling.
-During storage and handling, it is necessary to maintain a well-ventilated work area and avoid sparks and open flames.
Please note that this information is for informational purposes only and consult the relevant scientific literature and safety manuals before use for accurate information on nature, use and safety.
Nature:
-Appearance: 2-Thienylzinc bromide is a white to pale yellow solid.
-Solubility: Can be dissolved in organic solvents such as ether and dichloromethane.
-Stability: It is air-sensitive, so it needs to be treated under inert gas.
Use:
-Synthesis: 2-Thienylzinc bromide is an important reagent in organic synthesis. It can be used to synthesize other organic molecules, such as organometallic compounds or compounds containing thiophene groups.
-Catalyst: 2-Thienylzinc bromide is also used as a catalyst for cross-coupling reactions, such as the Tokner metal addition reaction.
Preparation Method:
- 2-Thienylzinc bromide can be prepared by reacting thiophene with ethyl zinc bromide. The thiophene was first reacted with copper iodide and then with ethylzinc bromide under an inert atmosphere to give finally 2-Thienylzinc bromide.
Safety Information:
Dust and vapours from the-2-Thienylzinc bromide may cause irritation and damage to the eyes, skin and respiratory system. Care should therefore be taken to avoid contact and inhalation.
-Wear appropriate protective gloves, goggles and protective mask during use and handling.
-During storage and handling, it is necessary to maintain a well-ventilated work area and avoid sparks and open flames.
Please note that this information is for informational purposes only and consult the relevant scientific literature and safety manuals before use for accurate information on nature, use and safety.
Last Update：2024-04-10 22:29:15
