4553-21-3
1-(2-Aminoethyl)-4-benzylpiperazine
CAS: 4553-21-3
Molecular Formula: C13H21N3
4553-21-3 - Names and Identifiers
| Name | 1-(2-Aminoethyl)-4-benzylpiperazine |
| Synonyms | AKOS BB-6126 4-Benzyl-1-piperazineethanamine 1-(AMINOEHTYL)-4-BENZYLPIPERAZINE 1-(2-Aminoethyl)-4-benzylpiperazine 2-(4-Benzylpiperazin-1-yl)ethanamine 4-Benzyl-1-piperazineethanamine 3HCl 1-Piperazineethanamine, 4-(phenylmethyl)- 1-(2-ammonioethyl)-4-benzylpiperazinediium 1-(2-Aminoethyl)-4-benzylpiperazine, {[4-(2-Aminoethyl)piperazin-1-yl]methyl}benzene |
| CAS | 4553-21-3 |
| InChI | InChI=1/C13H21N3/c14-6-7-15-8-10-16(11-9-15)12-13-4-2-1-3-5-13/h1-5H,6-12,14H2/p+3 |
4553-21-3 - Physico-chemical Properties
| Molecular Formula | C13H21N3 |
| Molar Mass | 219.33 |
| Density | 1.053±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 247℃ |
| Boling Point | 118 °C |
| Flash Point | 154.6°C |
| Vapor Presure | 0.000118mmHg at 25°C |
| pKa | 10.11±0.10(Predicted) |
| Sensitive | Air Sensitive |
4553-21-3 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37 - Wear suitable gloves. S24/25 - Avoid contact with skin and eyes. S23 - Do not breathe vapour. |
| HS Code | 29339900 |
| Hazard Note | Irritant |
4553-21-3 - Introduction
1-(2-Aminoethyl)-4-benzylpiperazine is an organic compound with the chemical formula C12H18N2. It is a white solid with a special amino and benzyl substituted piperazine structure.
The primary use of 1-(2-Aminoethyl)-4-benzylpiperazine is as a pharmaceutical intermediate. It can be used to synthesize a variety of biologically active compounds, especially in drug development has an important position. In addition, it can also be used in organic synthesis reactions and as a catalyst precursor.
A method for preparing 1-(2-Aminoethyl)-4-benzylpiperazine is generally obtained by reacting piperazine with 2-aminoethylbenzyl alcohol. A specific synthesis step may be reacting piperazine with sodium hydroxide and 2-aminoethyl benzyl alcohol in an appropriate solvent, and then purifying by crystallization to obtain the target product.
Regarding safety information, 1-(2-Aminoethyl)-4-benzylpiperazine is a chemical and needs to be handled in a laboratory environment and follow the corresponding safety procedures. During handling and storage, care should be taken to prevent contact with oxidants and strong acids. In addition, it is necessary to wear appropriate personal protective equipment, such as protective glasses, gloves and lab clothes. During use, try to avoid inhalation, swallowing or contact with skin. If accidental contact occurs, flush immediately with plenty of water and seek medical help. When dealing with waste, it is also necessary to dispose of it in accordance with relevant regulations. Overall, proper handling and storage minimizes risk.
The primary use of 1-(2-Aminoethyl)-4-benzylpiperazine is as a pharmaceutical intermediate. It can be used to synthesize a variety of biologically active compounds, especially in drug development has an important position. In addition, it can also be used in organic synthesis reactions and as a catalyst precursor.
A method for preparing 1-(2-Aminoethyl)-4-benzylpiperazine is generally obtained by reacting piperazine with 2-aminoethylbenzyl alcohol. A specific synthesis step may be reacting piperazine with sodium hydroxide and 2-aminoethyl benzyl alcohol in an appropriate solvent, and then purifying by crystallization to obtain the target product.
Regarding safety information, 1-(2-Aminoethyl)-4-benzylpiperazine is a chemical and needs to be handled in a laboratory environment and follow the corresponding safety procedures. During handling and storage, care should be taken to prevent contact with oxidants and strong acids. In addition, it is necessary to wear appropriate personal protective equipment, such as protective glasses, gloves and lab clothes. During use, try to avoid inhalation, swallowing or contact with skin. If accidental contact occurs, flush immediately with plenty of water and seek medical help. When dealing with waste, it is also necessary to dispose of it in accordance with relevant regulations. Overall, proper handling and storage minimizes risk.
Last Update：2024-04-09 21:32:41
