456-14-4

456-14-4 - Names and Identifiers

Name	4-Fluorobenzamidine hydrochloride
Synonyms	4-FLUOROBENZAMIDINE HCL 4-Fluorobenzamidine hydrochloride 4-FLUORO-BENZAMIDINE HYDROCHLORIDE 4-fluorobenzimidamide hydrochloride 4-Fluorobenzamidine Hydrochloride Hydrate amino(4-fluorophenyl)methaniminium chloride 4-fluorobenzene-1-carboxiMidaMide hydrochloride
CAS	456-14-4
InChI	InChI=1/C7H7FN2.ClH/c8-6-3-1-5(2-4-6)7(9)10;/h1-4H,(H3,9,10);1H

456-14-4 - Physico-chemical Properties

Molecular Formula	C7H8ClFN2
Molar Mass	174.6
Melting Point	209.0 to 213.0 °C
Boling Point	243.6°C at 760 mmHg
Flash Point	101.1°C
Vapor Presure	0.0255mmHg at 25°C
Appearance	Solid
Storage Condition	Inert atmosphere,Room Temperature

456-14-4 - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

456-14-4 - Introduction

4-Fluorobenzamidine hydrochloride is a compound with the chemical formula C7H7FN2 · HCl. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 4-Fluorobenzamidine hydrochloride is white crystal or crystalline powder.
-Solubility: Soluble in water and alcohol solvents.
-Melting point: about 207-211°C.

Use:
- 4-Fluorobenzamidine hydrochloride is a common reagent in organic synthesis and has a wide range of applications in pharmaceutical synthesis and organic synthesis.
-It can be used for angiotensin converting enzyme (ACE) inhibitor research.

Preparation Method:
- 4-Fluorobenzamidine hydrochloride can be prepared by the following steps: 4-fluorobenzylamine is first reacted with one equivalent of hydrochloric acid to obtain 4-fluorobenzylamine hydrochloride. 4-fluorobenzylamine hydrochloride is then reacted with one equivalent of nitroso mercury chloride to produce the 4-fluorobenzyl nitroso compound. Finally, the resulting nitroso compound is reacted with cyanchloride or hydrogen cyanide to give 4-Fluorobenzamidine hydrochloride.

Safety Information:
- 4-Fluorobenzamidine hydrochloride During use, care should be taken to avoid contact with skin, eyes and administration. Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during operation.
-In case of contact with 4-Fluorobenzamidine hydrochloride, immediately rinse the contact area with plenty of water and seek medical help.
-The compound should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.

Last Update：2024-04-09 21:00:56