4637-24-5
N,N-dimethyl for mamide dimethyl acctel
CAS: 4637-24-5
Molecular Formula: C5H13NO2
4637-24-5 - Names and Identifiers
4637-24-5 - Physico-chemical Properties
| Molecular Formula | C5H13NO2 |
| Molar Mass | 119.16 |
| Density | 0.897 g/mL at 25 °C (lit.) |
| Melting Point | -85°C |
| Boling Point | 102-103 °C/720 mmHg (lit.) |
| Flash Point | 45°F |
| Water Solubility | hydrolysis |
| Solubility | Miscible with most organic solvents. |
| Vapor Presure | 34.5hPa at 20℃ |
| Appearance | Solid |
| Color | White to off-white |
| Exposure Limit | ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)OSHA: TWA 200 ppm(260 mg/m3)NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3) |
| BRN | 506020 |
| pKa | 5.00±0.50(Predicted) |
| PH | 7 (H2O) |
| Storage Condition | Store below +30°C. |
| Sensitive | Moisture Sensitive |
| Explosive Limit | 1.3-17.7%(V) |
| Refractive Index | n20/D 1.396(lit.) |
| Use | Used as a drug zaleplon Intermediate |
4637-24-5 - Risk and Safety
| Risk Codes | R11 - Highly Flammable R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R36/38 - Irritating to eyes and skin. R20 - Harmful by inhalation R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R10 - Flammable R52 - Harmful to aquatic organisms |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S33 - Take precautionary measures against static discharges. S29 - Do not empty into drains. S7/9 - |
| UN IDs | UN 3271 3/PG 2 |
| WGK Germany | 1 |
| FLUKA BRAND F CODES | 21 |
| TSCA | Yes |
| HS Code | 29225000 |
| Hazard Class | 3 |
| Packing Group | II |
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg |
4637-24-5 - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Introduction | N-dimethylmethylmethylamine dimethylacetal, English name is N,N-Dimethylformamide dimethyl acetal, abbreviated as DMF-DMA. N,N-dimethylmethylamine dimethylacetal has a wide range of uses. It is an important intermediate for the synthesis of heterocyclic compounds. It is also a good methylation reagent and vinegar dehydrating agent, especially as an intermediate in pharmaceutical synthesis. It can be used for the synthesis of 1,2,3-trifolium, wainomum drugs, oxfloxacin, milrinone and other drugs. |
| Use | N,N-dimethylformamide dimethylacetal is used to synthesize pyridine derivatives with inhibitory effect Reagents, such derivatives have inhibitory effect on P13 kinase p110α enzyme. Used as the intermediate of drug zaleplon The intermediate of organic synthesis, pharmaceutical synthesis, and the precursor of formamidine synthesis. Preparation of 1,2,3-triketones and indole, quinolones. It can be used to synthesize ofloxacin, milrinone, allopurine and other drugs. Used as a drug zaleplon intermediate Used in the rearrangement reaction of various Claisen othro-ester; used to prepare formamidine derivatives; catalytically couple carbon dioxide and epoxy compounds under solvent-free conditions to synthesize cyclic carbonate |
| spontaneous combustion temperature | 155°C |
Last Update：2024-04-10 22:29:15
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View History
4637-24-5
2-(4-DIMETHYLAMINO-2-HYDROXY-BENZOYL)-BENZOIC ACID
titanium atomic spectroscopy standard concentrate 1.00 g ti
2-(Methylthio)Acetaldehyde Oxime
FMOC-3,4-二氯-D-高苯丙氨酸
Diphenyl anilinophosphonate
RuO2·2H2O
25441-04-7
Ethanimidic acid, 2,2,2-trichloro-, (2E,4E)-2,4-hexadien-1-yl ester
2-(4-DIMETHYLAMINO-2-HYDROXY-BENZOYL)-BENZOIC ACID
titanium atomic spectroscopy standard concentrate 1.00 g ti
2-(Methylthio)Acetaldehyde Oxime
FMOC-3,4-二氯-D-高苯丙氨酸
Diphenyl anilinophosphonate
RuO2·2H2O
25441-04-7
Ethanimidic acid, 2,2,2-trichloro-, (2E,4E)-2,4-hexadien-1-yl ester