47375-34-8
boc-O-tert-butyl-L-tyrosine
CAS: 47375-34-8
Molecular Formula: C18H27NO5
47375-34-8 - Names and Identifiers
| Name | boc-O-tert-butyl-L-tyrosine |
| Synonyms | BOC-TYR(TBU)-OH Boc-Tyr(But)-OH Boc-Tyr(tBu)-OH BOC-L-TYR(TBU)-OH BOC-TYROSINE(TBU)-OH BOC-O-T-BUTYL-L-TYROSINE boc-O-tert-butyl-L-tyrosine BOC-O-TERT-BUTYL-L-TYROSINE N-(tert-butoxycarbonyl)-O-tert-butyl-L-tyrosine (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(tert-butoxy)phenyl]propanoic acid (2S)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid |
| CAS | 47375-34-8 |
| InChI | InChI=1/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1 |
| InChIKey | ZEQLLMOXFVKKCN-AWEZNQCLSA-N |
47375-34-8 - Physico-chemical Properties
| Molecular Formula | C18H27NO5 |
| Molar Mass | 337.41 |
| Density | 1.116±0.06 g/cm3(Predicted) |
| Melting Point | 113-118°C |
| Boling Point | 484.0±40.0 °C(Predicted) |
| Specific Rotation(α) | -15 º (C=1% IN DMF) |
| Flash Point | 246.5°C |
| Water Solubility | Soluble in DMF. Insoluble in water. |
| Vapor Presure | 3.52E-10mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| BRN | 4327336 |
| pKa | 3.00±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.514 |
| MDL | MFCD00065598 |
47375-34-8 - Risk and Safety
| WGK Germany | 3 |
| HS Code | 29242990 |
47375-34-8 - Introduction
boc-O-tert-butyl-L-tyrosine is an organic compound whose chemical formula is C19H27NO5. The following is a description of the nature, use, preparation and safety information of the boc-O-tert-butyl-L-tyrosine:
Nature:
-Appearance: The boc-O-tert-butyl-L-tyrosine is white crystalline powder.
-Melting point: about 145-146 ℃.
-Solubility: Good solubility in some common organic solvents (such as dimethylformamide, acetonitrile and dichloromethane).
Use:
- boc-O-tert-butyl-L-tyrosine are commonly used as reagents and intermediates in organic synthesis.
-It has important applications in drug research and development, especially in the field of synthetic peptide drugs and protein engineering.
Preparation Method:
boc-O-tert-butyl-L-tyrosine can usually be synthesized by the following steps:
1. Boc-tyrosine is produced by reacting L-tyrosine with tert-butyric anhydride (Boc2O) in an alkaline environment.
2. Then, a tert-butyl protecting group (Boc) is introduced into the tyrosine molecule by a reaction using a reagent under acidic conditions to obtain boc-O-tert-butyl-L-tyrosine.
Safety Information:
- boc-O-tert-butyl-L-tyrosine should be stored in a dry, cool place, away from direct sunlight.
-Use appropriate personal protective equipment, such as lab gloves and goggles.
-As the boc-O-tert-butyl-L-tyrosine has not yet conducted an extensive toxicity assessment, please follow the correct laboratory operating procedures and conduct other relevant safety measures and risk assessments as needed.
Nature:
-Appearance: The boc-O-tert-butyl-L-tyrosine is white crystalline powder.
-Melting point: about 145-146 ℃.
-Solubility: Good solubility in some common organic solvents (such as dimethylformamide, acetonitrile and dichloromethane).
Use:
- boc-O-tert-butyl-L-tyrosine are commonly used as reagents and intermediates in organic synthesis.
-It has important applications in drug research and development, especially in the field of synthetic peptide drugs and protein engineering.
Preparation Method:
boc-O-tert-butyl-L-tyrosine can usually be synthesized by the following steps:
1. Boc-tyrosine is produced by reacting L-tyrosine with tert-butyric anhydride (Boc2O) in an alkaline environment.
2. Then, a tert-butyl protecting group (Boc) is introduced into the tyrosine molecule by a reaction using a reagent under acidic conditions to obtain boc-O-tert-butyl-L-tyrosine.
Safety Information:
- boc-O-tert-butyl-L-tyrosine should be stored in a dry, cool place, away from direct sunlight.
-Use appropriate personal protective equipment, such as lab gloves and goggles.
-As the boc-O-tert-butyl-L-tyrosine has not yet conducted an extensive toxicity assessment, please follow the correct laboratory operating procedures and conduct other relevant safety measures and risk assessments as needed.
Last Update：2024-04-09 21:04:16
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Product Name: Boc-Tyr(tBu)-OH Visit Supplier Webpage Request for quotationCAS: 47375-34-8
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