480424-82-6
[3-(1-Piperidinylmethyl)phenyl]magnesium bromide
CAS: 480424-82-6
Molecular Formula: C6H4CH2NC5H10MgBr
480424-82-6 - Names and Identifiers
480424-82-6 - Physico-chemical Properties
| Molecular Formula | C6H4CH2NC5H10MgBr |
| Molar Mass | 278.47 |
| Density | 0.919g/mLat 25°C |
| Boling Point | 65°C |
| Flash Point | 1°F |
| Storage Condition | 2-8°C |
480424-82-6 - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R34 - Causes burns R40 - Limited evidence of a carcinogenic effect R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2924 3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29310099 |
480424-82-6 - Introduction
[3-(1-Piperidinylmethyl)phenyl]magnesium bromide is an organomagnesium compound with the chemical formula C12H15BrMgN. It is a white crystalline powder. [3-(1-Piperidinylmethyl)phenyl]magnesium bromide is an organic reagent commonly used in Grignard reagents and olefin reduction reactions in organic synthesis. It can reduce ketones or aldehydes to the corresponding alcohols and is highly stereoselective. In addition, it can be used to synthesize other bromides and organometallic compounds.
Preparation of [3-(1-Piperidinylmethyl)phenyl]magnesium bromide is generally prepared by reacting 3-(1-piperidinylmethyl) phenyl halide (e. g., 3-(1-piperidinylmethyl) bromobenzene) with metallic magnesium in diethyl ether or tetrahydrofuran. The reaction conditions generally need to be kept dry to avoid reaction with water.
Regarding safety information, [3-(1-Piperidinylmethyl)phenyl]magnesium bromide is an organic magnesium reagent with strong reducibility. During operation, care should be taken to avoid contact with air, water, acids and other oxidants. In addition, pay attention to its flammability and irritation, and wear appropriate protective equipment such as gloves, goggles and protective clothing during operation.
Preparation of [3-(1-Piperidinylmethyl)phenyl]magnesium bromide is generally prepared by reacting 3-(1-piperidinylmethyl) phenyl halide (e. g., 3-(1-piperidinylmethyl) bromobenzene) with metallic magnesium in diethyl ether or tetrahydrofuran. The reaction conditions generally need to be kept dry to avoid reaction with water.
Regarding safety information, [3-(1-Piperidinylmethyl)phenyl]magnesium bromide is an organic magnesium reagent with strong reducibility. During operation, care should be taken to avoid contact with air, water, acids and other oxidants. In addition, pay attention to its flammability and irritation, and wear appropriate protective equipment such as gloves, goggles and protective clothing during operation.
Last Update：2024-04-10 22:29:15
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