4837-20-1
4-(difluoromethoxy)benzoic acid
CAS: 4837-20-1
Molecular Formula: C8H6F2O3
4837-20-1 - Names and Identifiers
| Name | 4-(difluoromethoxy)benzoic acid |
| Synonyms | AKOS B006807 RARECHEM AL BO 0735 TIMTEC-BB SBB003678 4-(difluoromethoxy)benzoate 4-(DIFLUOROMETHOXY)BENZOIC ACID P-(DIFLUOROMETHOXY)BENZOIC ACID 4-(difluoromethoxy)benzoic acid 4-(Difluorome4-(Difluoromethoxy)benzoic acidthoxy)benzoic acid |
| CAS | 4837-20-1 |
| EINECS | 625-589-7 |
| InChI | InChI=1/C8H6F2O3/c9-8(10)13-6-3-1-5(2-4-6)7(11)12/h1-4,8H,(H,11,12)/p-1 |
4837-20-1 - Physico-chemical Properties
| Molecular Formula | C8H6F2O3 |
| Molar Mass | 188.13 |
| Density | 1.370±0.06 g/cm3(Predicted) |
| Melting Point | 169-171 °C (lit.) |
| Boling Point | 272.1±30.0 °C(Predicted) |
| Flash Point | 118.3°C |
| Vapor Presure | 0.00304mmHg at 25°C |
| BRN | 2615223 |
| pKa | 4.02±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| MDL | MFCD00221454 |
4837-20-1 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29189900 |
| Hazard Class | IRRITANT |
4837-20-1 - Introduction
4-(difluoromethoxy)benzoic acid is an organic compound with the chemical formula C8H6F2O3. It is a colorless to pale yellow solid with a peculiar odor.
One of the main uses of this compound is as a pharmaceutical intermediate. It can be used to synthesize anti-inflammatory, analgesic and anti-tuberculosis drugs. In addition, it can also be used as a raw material for paints and dyes.
The method for preparing 4-(difluoromethoxy)benzoic acid is mainly obtained by reacting 3,4-difluoroanisole with carbon dioxide. The specific synthesis process can be carried out by different methods, such as using an ether solvent to catalyze the reaction, or using a gas phase method to carry out the reaction.
As with any chemical, safety precautions are required when using and handling 4-(difluoromethoxy)benzoic acid. It is an irritating chemical, and inhalation of its dust or gas should be avoided. Wear appropriate protective equipment such as goggles and chemical protective gloves during operation. When storing and handling compounds, care should be taken to avoid high temperatures and open flames, and to store them in sealed containers, away from acids, alkalis, and oxidants. During use and handling, it is necessary to follow appropriate procedures and safe operating procedures. In the laboratory, it is recommended to use the compound under the guidance of a professional.
One of the main uses of this compound is as a pharmaceutical intermediate. It can be used to synthesize anti-inflammatory, analgesic and anti-tuberculosis drugs. In addition, it can also be used as a raw material for paints and dyes.
The method for preparing 4-(difluoromethoxy)benzoic acid is mainly obtained by reacting 3,4-difluoroanisole with carbon dioxide. The specific synthesis process can be carried out by different methods, such as using an ether solvent to catalyze the reaction, or using a gas phase method to carry out the reaction.
As with any chemical, safety precautions are required when using and handling 4-(difluoromethoxy)benzoic acid. It is an irritating chemical, and inhalation of its dust or gas should be avoided. Wear appropriate protective equipment such as goggles and chemical protective gloves during operation. When storing and handling compounds, care should be taken to avoid high temperatures and open flames, and to store them in sealed containers, away from acids, alkalis, and oxidants. During use and handling, it is necessary to follow appropriate procedures and safe operating procedures. In the laboratory, it is recommended to use the compound under the guidance of a professional.
Last Update：2024-04-09 20:52:54
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CAS: 4837-20-1
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