484064-96-2
propargyl carbonate N-hydroxysuccinimide ester
CAS: 484064-96-2
Molecular Formula: C8H7NO5
484064-96-2 - Names and Identifiers
| Name | propargyl carbonate N-hydroxysuccinimide ester |
| Synonyms | PROC-OSU Proc-Osu propargyl carbonate N-hydroxysuccinimide ester 2,5-dioxopyrrolidin-1-yl prop-2-yn-1-yl carbonate |
| CAS | 484064-96-2 |
484064-96-2 - Physico-chemical Properties
| Molecular Formula | C8H7NO5 |
| Molar Mass | 197.14 |
484064-96-2 - Introduction
carbonate N-hydroxysuccinimide propargyl (N-hydroxysuccinimide ester) is a chemical reagent whose properties are as follows:
1. Appearance: white crystalline solid
2. molecular formula: C11H9N2O5
3. Molecular weight: 247.20g/mol
4. melting point: 130-133 ℃
5. Solubility: Soluble in most organic solvents such as dimethyl sulfoxide and dichloromethane
propargyl carbonate N-hydroxysuccinimide ester is mainly used in the fields of biochemistry, medicinal chemistry and organic synthesis, and has the following uses:
1. Coupling reagent: propargyl carbonate N-hydroxysuccinimide ester can react with compounds containing active hydroxyl groups (such as amino acids, peptides and proteins) to form ester bonds, which are used to prepare compounds with specific functions.
2. Chemical modification: propargyl carbonate N-hydroxysuccinimide ester can be used to introduce protecting groups or labeling groups to modify biological molecules, change their properties or study their structure and function.
3. drug synthesis: propargyl carbonate N-hydroxysuccinimide ester is often used to construct carbon chains in drug synthesis, introducing specific functional groups or protecting active groups.
The preparation method of propargyl carbonate N-hydroxysuccinimide ester is relatively simple. A common preparation method is to combine N-hydroxysuccinimide ester (N-hydroxysuccinimide ester) and 2-propynyloxycarbonyl propionate (propargyl carbonate) Under alkaline conditions, the propargyl carbonate N-hydroxysuccinimide ester is generated.
Because propargyl carbonate N-hydroxysuccinimide ester is a chemical reagent, use caution. Here are some safety information:
1. propargyl carbonate N-hydroxysuccinimide ester may be irritating to the eyes, skin and respiratory tract. Avoid contact when using. Appropriate personal protective equipment such as gloves, goggles and protective masks should be worn.
2. avoid inhalation or intake of propargyl carbonate N-hydroxysuccinimide ester, such as ingestion or inhalation should seek medical advice immediately.
3. when using and storing propargyl carbonate N-hydroxysuccinimide ester, keep away from fire and avoid contact with flammable substances.
4. waste treatment: propargyl carbonate N-hydroxysuccinimide ester and its waste should be disposed in accordance with local regulations, and should not be dumped or discharged into water sources or the environment.
1. Appearance: white crystalline solid
2. molecular formula: C11H9N2O5
3. Molecular weight: 247.20g/mol
4. melting point: 130-133 ℃
5. Solubility: Soluble in most organic solvents such as dimethyl sulfoxide and dichloromethane
propargyl carbonate N-hydroxysuccinimide ester is mainly used in the fields of biochemistry, medicinal chemistry and organic synthesis, and has the following uses:
1. Coupling reagent: propargyl carbonate N-hydroxysuccinimide ester can react with compounds containing active hydroxyl groups (such as amino acids, peptides and proteins) to form ester bonds, which are used to prepare compounds with specific functions.
2. Chemical modification: propargyl carbonate N-hydroxysuccinimide ester can be used to introduce protecting groups or labeling groups to modify biological molecules, change their properties or study their structure and function.
3. drug synthesis: propargyl carbonate N-hydroxysuccinimide ester is often used to construct carbon chains in drug synthesis, introducing specific functional groups or protecting active groups.
The preparation method of propargyl carbonate N-hydroxysuccinimide ester is relatively simple. A common preparation method is to combine N-hydroxysuccinimide ester (N-hydroxysuccinimide ester) and 2-propynyloxycarbonyl propionate (propargyl carbonate) Under alkaline conditions, the propargyl carbonate N-hydroxysuccinimide ester is generated.
Because propargyl carbonate N-hydroxysuccinimide ester is a chemical reagent, use caution. Here are some safety information:
1. propargyl carbonate N-hydroxysuccinimide ester may be irritating to the eyes, skin and respiratory tract. Avoid contact when using. Appropriate personal protective equipment such as gloves, goggles and protective masks should be worn.
2. avoid inhalation or intake of propargyl carbonate N-hydroxysuccinimide ester, such as ingestion or inhalation should seek medical advice immediately.
3. when using and storing propargyl carbonate N-hydroxysuccinimide ester, keep away from fire and avoid contact with flammable substances.
4. waste treatment: propargyl carbonate N-hydroxysuccinimide ester and its waste should be disposed in accordance with local regulations, and should not be dumped or discharged into water sources or the environment.
Last Update：2024-04-09 21:04:16
