490-31-3
Robinetin
CAS: 490-31-3
Molecular Formula: C15H10O7
490-31-3 - Names and Identifiers
| Name | Robinetin |
| Synonyms | Robinetin ROBINETIN norkanugin 5-HYDROXYFISETIN 3,3',4',5',7-pentahydroxy-flavon 3,7,3',4',5'-PENTAHYDROXYFLAVONE 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4-benzopyrone 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl-4H-1-benzopyran-4-one) (Robinetin) |
| CAS | 490-31-3 |
| EINECS | 207-709-6 |
490-31-3 - Physico-chemical Properties
| Molecular Formula | C15H10O7 |
| Molar Mass | 302.24 |
| Density | 1.3616 (rough estimate) |
| Melting Point | 326-328°C |
| Boling Point | 363.28°C (rough estimate) |
| Solubility | DMSO (Sparingly), Methanol (Slightly, Heated) |
| Appearance | Yellow powder |
| Color | Yellow to Dark Yellow |
| pKa | 6.82±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4790 (estimate) |
| In vitro study | Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner. Robinetin inhibits the DNA synthesis in Proteus vulgaris , and the RNA synthesis in S. aureus . Robinetin (100-200 or 25 μM; 1 or 72 h) inhibits egg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore. |
490-31-3 - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | S22 - Do not breathe dust. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2811 |
490-31-3 - Reference Information
| biological activity | Robinetin (3,3 ',4',5 ',7-Pentahydroxyflavone) is a natural flavonoid, has significant "two colors" intrinsic fluorescence properties, with antifungal, antiviral, antibacterial, antimutagenic and antioxidant activity. Robinetin can also inhibit lipid peroxidation and protein glycosylation. |
Last Update：2024-04-09 21:11:58
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