49674-16-0
3-Amino-5-bromobenzonitrile
CAS: 49674-16-0
Molecular Formula: C7H5BrN2
49674-16-0 - Names and Identifiers
| Name | 3-Amino-5-bromobenzonitrile |
| Synonyms | 3-Bromo-5-cyanoaniline 5-AMINO-3-BROMOBENZONITRILE 3-Amino-5-bromobenzonitrile 5-Amino-3-bromobenzonitrile Benzonitrile, 3-amino-5-bromo- |
| CAS | 49674-16-0 |
| InChI | InChI=1/C7H5BrN2/c8-6-1-5(4-9)2-7(10)3-6/h1-3H,10H2 |
49674-16-0 - Physico-chemical Properties
| Molecular Formula | C7H5BrN2 |
| Molar Mass | 197.04 |
| Density | 1.68±0.1 g/cm3(Predicted) |
| Boling Point | 320.2±22.0 °C(Predicted) |
| Flash Point | 147.5°C |
| Vapor Presure | 0.000323mmHg at 25°C |
| pKa | 1.72±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.652 |
49674-16-0 - Introduction
It is an organic compound with the chemical formula C7H4BrN2. It is white or light yellow crystals with a special smell. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White or light yellow crystal
-Solubility: Soluble in many organic solvents, such as ethanol, dimethylformamide
-melting point: about 140-145 ℃
-Density: approx. 1.72g/cm³
Use:
It is often used as an intermediate in organic synthesis and can be used to synthesize other drugs, pesticides or dyes. It can also be used as an important raw material in the field of chemical synthesis and research.
Preparation Method:
A common preparation method is by bromination of benzonitrile and then substitution reaction with ammonia. Specific steps are as follows:
1. dissolve benzonitrile in bromine water with acetic acid mass fraction of 30%, stir and heat.
2. As the bromination reaction proceeds, the interconnected ammonia gas is gradually added.
3. After the reaction is completed, the crystal product is obtained by water rinsing and crystallization.
Safety Information:
During operation, attention should be paid to protective measures, such as wearing protective glasses and gloves. In addition, the metal should be stored in a closed container, away from fire and oxidizing agents. Try to avoid skin contact and inhalation of dust or gas. In the case of accidental contact or misuse, seek immediate medical attention for professional help and bring a chemical label and relevant documentation.
Nature:
-Appearance: White or light yellow crystal
-Solubility: Soluble in many organic solvents, such as ethanol, dimethylformamide
-melting point: about 140-145 ℃
-Density: approx. 1.72g/cm³
Use:
It is often used as an intermediate in organic synthesis and can be used to synthesize other drugs, pesticides or dyes. It can also be used as an important raw material in the field of chemical synthesis and research.
Preparation Method:
A common preparation method is by bromination of benzonitrile and then substitution reaction with ammonia. Specific steps are as follows:
1. dissolve benzonitrile in bromine water with acetic acid mass fraction of 30%, stir and heat.
2. As the bromination reaction proceeds, the interconnected ammonia gas is gradually added.
3. After the reaction is completed, the crystal product is obtained by water rinsing and crystallization.
Safety Information:
During operation, attention should be paid to protective measures, such as wearing protective glasses and gloves. In addition, the metal should be stored in a closed container, away from fire and oxidizing agents. Try to avoid skin contact and inhalation of dust or gas. In the case of accidental contact or misuse, seek immediate medical attention for professional help and bring a chemical label and relevant documentation.
Last Update：2024-04-09 20:52:54
