5,10,15,20-TETRAKIS-(4-CARBOXYPHENYL)-21,23H-PORPHYRIN

5,10,15,20-TETRAKIS-(4-CARBOXYPHENYL)-21,23H-PORPHYRIN - Names and Identifiers

Name	meso-Tetra(4-carboxyphenyl)porphine
Synonyms	NICKEL IONOPHORE II RARECHEM AS SA 0048 TETRACARBOXYPHENYLPORPHYRIN TETRAKIS(4-CARBOXYPHENYL)PORPHINE MESO-TETRA(4-CARBOXYPHENYL)PORPHINE meso-Tetra(4-carboxyphenyl)porphine 5,10,15,20-TETRA(4-CARBOXYPHENYL)PORPHYRIN 5,10,15,20-TETRAKIS-(4-CARBOXYPHENYL)-21,23H-PORPHYRIN 4,4',4'',4'''-porphyrin-5,10,15,20-tetrayltetrabenzoic acid MESO-TETRAPHENYLPORPHINE-4,4',4'',4'''-TETRACARBOXYLIC ACID 4,4,4,4-(Porphine-5,10,15,20-tetrayl)tetrakis(benzoic acid)
CAS	14609-54-2
InChI	InChI=1/C48H30N4O8/c53-45(54)29-9-1-25(2-10-29)41-33-17-19-35(49-33)42(26-3-11-30(12-4-26)46(55)56)37-21-23-39(51-37)44(28-7-15-32(16-8-28)48(59)60)40-24-22-38(52-40)43(36-20-18-34(41)50-36)27-5-13-31(14-6-27)47(57)58/h1-24,49,52H,(H,53,54)(H,55,56)(H,57,58)(H,59,60)/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-

5,10,15,20-TETRAKIS-(4-CARBOXYPHENYL)-21,23H-PORPHYRIN - Physico-chemical Properties

Molecular Formula	C48H30N4O8
Molar Mass	790.77
Density	1.462±0.06 g/cm3(Predicted)
Melting Point	>300 °C
Appearance	Purple powder
Color	purple
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.734
MDL	MFCD00064860
Use	Ultra-high sensitive spectrophotometric reagents for copper and cadmium; used for simultaneous determination of metals with high performance liquid chromatography

5,10,15,20-TETRAKIS-(4-CARBOXYPHENYL)-21,23H-PORPHYRIN - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
RTECS	DH6488300

5,10,15,20-TETRAKIS-(4-CARBOXYPHENYL)-21,23H-PORPHYRIN - Reference

Reference

1. [IF=7.711] Rong Zhang et al."A Disposable Printed Liquid Gate Graphene Field Effect Transistor for a Salivary Cortisol Test."Acs Sensors. 2021;6(8):3024–3031
2. [IF=6.331] Xiao Liang et al."Urate oxidase loaded in PCN-222(Fe) with peroxidase-like activity for colorimetric detection of uric acid."J Mater Chem B. 2021 Sep;9(34):6811-6817
3. [IF=18.808] Xiu Zhao et al."Intracellular Self-Assembly Driven Nucleus-Targeted Photo-Immune Stimulator with Chromatin Decompaction Function for Robust Innate and Adaptive Antitumor Immunity."Adv Funct Mater. 2022 Apr;32(17):2108883
4. [IF=30.849] Jinjin Shi et al."Intracellular self-assembly driven uninterrupted ROS generator augments 5-aminolevulinic acid-based tumor therapy."ADVANCED MATERIALS

5,10,15,20-TETRAKIS-(4-CARBOXYPHENYL)-21,23H-PORPHYRIN - Reference Information

Overview	Medium-tetra (4-carboxyphenyl) porphin belongs to porphyrin compounds and is an organic chemical raw material.
synthesis method	synthesis of medium-tetra (4-carboxyphenyl) porin: add 150 mL propionic acid, 2.8 mL pyrrole and 6.57g methyl p-toluic acid into a 500 mL round bottom flask, heat and reflux reaction in a dark environment for 30 min, cool the reaction liquid to room temperature, filter, the filtered solid is sequentially washed with 1mol/L KOH aqueous solution and 1mol/L hydrochloric acid (the filtered solid is medium-tetra (4-carboxyphenyl) chlorin tetramethyl ester, and the ester is converted into potassium salt after KOH treatment, and the potassium salt is converted into carboxylic acid after HCl treatment) to obtain medium-tetra (4-carboxyphenyl) chlorin.
biological activity	Tetrakis (4-carboxyphenyl) porphyrin (TCPP) can be used as metal remover.
Uses	Ultra-high sensitive spectrophotometric reagents for copper and cadmium for simultaneous determination of metals with high performance liquid chromatography A nickel ion selective porphyrin sensor.
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)

Last Update：2024-04-10 22:29:15