5,6-diMethoxy-2,3-dihydro-1H-indole
5,6-dimethoxy-2,3-dihydro-1H-indole
CAS: 15937-07-2
Molecular Formula: C10H13NO2
5,6-diMethoxy-2,3-dihydro-1H-indole - Names and Identifiers
| Name | 5,6-dimethoxy-2,3-dihydro-1H-indole |
| Synonyms | 5,6-Dimethoxyindoline 5,6-DiMethoxyindoline 5,6-diMethoxy-2,3-dihydro-1H-indole 5,6-dimethoxy-2,3-dihydro-1H-indole 2,3-dihydro-5,6-diMethoxy-1H-Indole 1H-INDOLE, 2,3-DIHYDRO-5,6-DIMETHOXY 1H-indole, 2,3-dihydro-5,6-dimethoxy- 6-broMo-7-MethyliMidazo[1,2-b]pyridazine |
| CAS | 15937-07-2 |
| InChI | InChI=1/C10H13NO2/c1-12-9-5-7-3-4-11-8(7)6-10(9)13-2/h5-6,11H,3-4H2,1-2H3 |
5,6-diMethoxy-2,3-dihydro-1H-indole - Physico-chemical Properties
| Molecular Formula | C10H13NO2 |
| Molar Mass | 179.22 |
| Density | 1.102±0.06 g/cm3(Predicted) |
| Melting Point | 105℃ (benzene ) |
| Boling Point | 301.2±42.0 °C(Predicted) |
| Flash Point | 116.88°C |
| Vapor Presure | 0.001mmHg at 25°C |
| pKa | 5.72±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.534 |
5,6-diMethoxy-2,3-dihydro-1H-indole - Introduction
5,6-dimethoxy-2,3-dihydro-1H-indole, also known as DMIL, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
5,6-dimethoxy-2,3-dihydro-1H-indole is a yellow to orange crystalline solid. It is soluble in organic solvents such as methylene chloride and dimethyl sulfoxide at normal temperature. It has high thermal and chemical stability.
Use:
5,6-dimethoxy-2,3-dihydro-1H-indole is commonly used as a reagent in organic synthesis. It can be used as a catalyst, ligand or intermediate, and play an important role in organic synthesis reactions. It is widely used in metal organic chemistry, drug synthesis and materials science and other fields.
Method:
The preparation of 5,6-dimethoxy-2,3-dihydro-1H-indole is usually achieved by the amine methylation reaction of indole. A common method is to react indole with a solution of methanol and methyl chloride over a catalyst to give 5,6-dimethoxy-2,3-dihydro-1h-indole.
Safety Information:
5,6-dimethoxy-2,3-dihydro-1H-indole has limited safety information. Regular laboratory safety practices need to be followed during use and storage. Vigorous reactions with strong oxidants and high temperatures should be avoided. In addition, in order to avoid any potential risks, please read the relevant safety instructions and operating manuals. When using or handling this compound, it is recommended to wear appropriate protective equipment, such as gloves, protective glasses, and laboratory coats. If contact with skin or eyes is made, rinse immediately with plenty of water and seek medical help.
Nature:
5,6-dimethoxy-2,3-dihydro-1H-indole is a yellow to orange crystalline solid. It is soluble in organic solvents such as methylene chloride and dimethyl sulfoxide at normal temperature. It has high thermal and chemical stability.
Use:
5,6-dimethoxy-2,3-dihydro-1H-indole is commonly used as a reagent in organic synthesis. It can be used as a catalyst, ligand or intermediate, and play an important role in organic synthesis reactions. It is widely used in metal organic chemistry, drug synthesis and materials science and other fields.
Method:
The preparation of 5,6-dimethoxy-2,3-dihydro-1H-indole is usually achieved by the amine methylation reaction of indole. A common method is to react indole with a solution of methanol and methyl chloride over a catalyst to give 5,6-dimethoxy-2,3-dihydro-1h-indole.
Safety Information:
5,6-dimethoxy-2,3-dihydro-1H-indole has limited safety information. Regular laboratory safety practices need to be followed during use and storage. Vigorous reactions with strong oxidants and high temperatures should be avoided. In addition, in order to avoid any potential risks, please read the relevant safety instructions and operating manuals. When using or handling this compound, it is recommended to wear appropriate protective equipment, such as gloves, protective glasses, and laboratory coats. If contact with skin or eyes is made, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 20:52:54
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