5,7-DIHYDROXYFLAVONE
Chrysin
CAS: 480-40-0
Molecular Formula: C15H10O4
5,7-DIHYDROXYFLAVONE - Names and Identifiers
| Name | Chrysin |
| Synonyms | CHRYSIN Chrysin CHRYSINE AKOS NCG1-0026 5,7-Dihydroxyflavone 5,7-DIHYDROXYFLAVONE LABOTEST-BB LT00440772 Chrysin-5,7-dihydroxy Flavone 5,7-DIHYDROXY-2-PHENYL-CHROMEN-4-ONE 5,7-dihydroxy-2-phenyl-4H-chromen-4-one 5,7-dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one 5,7-dihydroxy-2-phenyl-4h-benzo[b]pyran-4-one |
| CAS | 480-40-0 |
| EINECS | 207-549-7 |
| InChI | InChI=1/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H |
| InChIKey | RTIXKCRFFJGDFG-UHFFFAOYSA-N |
5,7-DIHYDROXYFLAVONE - Physico-chemical Properties
| Molecular Formula | C15H10O4 |
| Molar Mass | 254.24 |
| Density | 1.2693 (rough estimate) |
| Melting Point | 284-286°C(lit.) |
| Boling Point | 357.45°C (rough estimate) |
| Flash Point | 192.5°C |
| Solubility | Slightly soluble in alkali hydroxide solution, dissolved acetone at room temperature, slightly soluble in ether, ethanol and chloroform, insoluble in water. |
| Vapor Presure | 2.67E-10mmHg at 25°C |
| Appearance | Pale yellow prismatic crystal |
| Color | Yellow |
| Merck | 14,2256 |
| BRN | 233276 |
| pKa | 6.50±0.40(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.4872 (estimate) |
| MDL | MFCD00006834 |
| Physical and Chemical Properties | Melting point 285-286°C |
| Use | It is a raw material for the synthesis of anticancer, hypolipidemic, anti-cardiovascular and cerebrovascular diseases, antibacterial, anti-inflammatory and other drugs |
5,7-DIHYDROXYFLAVONE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | LK8329050 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29329990 |
| Hazard Class | IRRITANT |
5,7-DIHYDROXYFLAVONE - Reference Information
| introduction | aspen exists in the seeds and stems of the wood butterfly [Oroxylum indicum(L.)Vent.] of the Bignoniaceae plant, the heart tree of the Pinus mon-ticola Dougl., and the heart tree of the Pinus pine (P.aristata Engelm.). |
| pharmacological effects | modern pharmacological studies have shown that chrydonin has a wide range of pharmacological activities, such as anti-tumor effects; Anti-allergic effects; Anti-inflammatory effects; Anti-viral effects; Anti-pathogenic microbial effects and hypoglycemic effects, etc. Drugs with chrycein as the main active ingredient have been used in many countries and regions. A variety of derivatives obtained by structural modification with chronin as the lead compound also show that they have relatively good or better pharmacological activities. |
| use | synthesis of anti-cancer, hypolipidemic, anti-cardiovascular and cerebrovascular diseases, antibacterial, anti-inflammatory and other pharmaceutical raw materials. A flavonoid, similar to apigenin. It inhibits aromatase and also inhibits HIV activation in latent infection models. The element has anti-inflammatory and antioxidant effects. Various cell apoptosis is induced, thereby exhibiting anti-cancer chemoprevention activity. is a raw material for synthesizing anti-cancer, lowering blood lipids, preventing cardiovascular and cerebrovascular diseases, antibacterial, anti-inflammatory and other drugs |
Last Update：2024-04-09 21:22:08
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