Name | 5,7-Dibromo-8-hydroxyquinoline |
Synonyms | Brodiar Colipar Colepur Bromoxin Broxykinolin Broxyquinolin Broxiquinoline Broxyquinoline 5,7-Dibromo-8-quinolinol 5,7-dibromoquinolin-8-ol 8-Quinolinol, 5,7-dibromo- 5,7-Dibromo-8-oxyquinoline 5,7-Dibromo-8-hydroxyquinoline 5,7-dibromo-8-hydroxy quinoline |
CAS | 521-74-4 |
EINECS | 208-317-8 |
InChI | InChI=1/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H |
Molecular Formula | C9H5Br2NO |
Molar Mass | 302.95 |
Density | 2.189 |
Melting Point | 198-200°C(lit.) |
Boling Point | 363.74°C (rough estimate) |
Flash Point | 177.9°C |
Solubility | DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated) |
Vapor Presure | 5.15E-06mmHg at 25°C |
Appearance | Solid |
Color | Off-White to Pale Beige |
Merck | 14,1453 |
BRN | 153624 |
pKa | 2.23±0.30(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Sensitive | Sensitive to light |
Refractive Index | 1.6400 (estimate) |
MDL | MFCD00006785 |
Physical and Chemical Properties | There are bright white needle-like crystals. Melting point 196 °c (200-201 °c). Soluble in concentrated acid, benzene, ether and carbon disulfide, ethanol-soluble, almost insoluble in water and dilute acid. Can sublimate. |
Use | Used as an analytical reagent |
In vitro study | Broxyquinoline inhibits the binding of CpACBP1 to NBD-palmitoyl-CoA. Broxyquinoline also had an inhibitory effect on the in vitro activity of prolyl and asparagine hydroxylation of HIF-1α. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 2 |
RTECS | VC5300000 |
FLUKA BRAND F CODES | 8 |
TSCA | Yes |
HS Code | 29334900 |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
biological activity | Broxyquinoline is an antigenic insect that acts on the mucosa and can release oxygen free radicals from water. |
Use | Used as an analytical reagent |
Production method | It is obtained by bromination of 8-hydroxyquinoline. |