5,7-Difluoroquinoline - Names and Identifiers
5,7-Difluoroquinoline - Physico-chemical Properties
Molecular Formula | C9H5F2N
|
Molar Mass | 165.14 |
Density | 1.319 |
Boling Point | 235℃ |
Flash Point | 96℃ |
Vapor Presure | 0.0783mmHg at 25°C |
Appearance | Brown powder |
pKa | 2.82±0.26(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.588 |
5,7-Difluoroquinoline - Introduction
5,7-Difluoroquinoline is an organic compound with the chemical formula C9H5F2N. The following is a description of the nature, use, preparation and safety information of 5,7-Difluoroquinoline:
Nature:
- 5,7-Difluoroquinoline is a colorless or slightly yellow solid.
-Its melting point is about 82-84°C.
- 5,7-Difluoroquinoline is almost insoluble in water at room temperature, but can be dissolved in some organic solvents.
Use:
- 5,7-Difluoroquinoline can be used as a pharmaceutical intermediate for the synthesis of various biologically active compounds.
-It can also be used as a synthetic raw material for dyes, coatings and optical materials.
Preparation Method:
- 5,7-Difluoroquinoline has many preparation methods, one of which is commonly used by reacting 1,5-difluoroquinoline with anthranilic acid.
-In this reaction, 1,5-difluoroquinoline is first treated with alkali to generate the corresponding acid salt, and then esterified with anthranilic acid to finally obtain 5,7-Difluoroquinoline.
Safety Information:
- 5,7-Difluoroquinoline is generally stable under normal conditions of use, but contact with strong oxidants or oxygen should be avoided to prevent unsafe reactions.
-During operation, care should be taken to avoid inhalation, ingestion or contact with skin and eyes. Personal protective equipment such as gloves, goggles and protective clothing should be worn.
-If you come into contact with this compound, rinse the affected area immediately with plenty of water and seek medical attention.
Last Update:2024-04-09 02:00:45