5,7-dichloro-2-methylquinolin-8-ol
5,7-Dichloro-8-quinaldinol
CAS: 72-80-0
Molecular Formula: C10H7Cl2NO
5,7-dichloro-2-methylquinolin-8-ol - Names and Identifiers
| Name | 5,7-Dichloro-8-quinaldinol |
| Synonyms | Clorquinaldol Chlorquinalol Chlorchinaldol Chlorquinaldol Chloroquinaldol CHLORQUINALDOL(RG) 5,7-DICHLORO-8-QUINALDOL 5,7-Dichloro-8-quinaldinol 5,7-Dichloro-8-hydroxyquinaldine 5,7-DICHLORO-8-HYDROXYQUINALIDNE 5,7-Dichloro-8-hydroxyquinalidine 5,7-dichloro-2-methylquinolin-8-ol 5,7-Dichloro-8-hydroxy-2-methylquinoline 5,7-Dichloro-2-methyl-8-hydroxyquinoline 2-METHYL-5,7-DICHLORO-8-HYDROXYQUINOLINE |
| CAS | 72-80-0 |
| EINECS | 200-789-3 |
| InChI | InChI=1/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3 |
5,7-dichloro-2-methylquinolin-8-ol - Physico-chemical Properties
| Molecular Formula | C10H7Cl2NO |
| Molar Mass | 228.07 |
| Density | 1.3126 (rough estimate) |
| Melting Point | 108-112°C (dec.)(lit.) |
| Boling Point | 350.7±37.0 °C(Predicted) |
| Flash Point | 165.9°C |
| Water Solubility | Insoluble |
| Solubility | DMSO, Methaol (Slightly) |
| Vapor Presure | 2.13E-05mmHg at 25°C |
| Appearance | Solid |
| Color | Dark Beige to Very Dark Beige |
| Merck | 13,2209 |
| BRN | 156683 |
| pKa | 2.47±0.30(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.5500 (estimate) |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | Chlorquinaldol is a derivative of hydroxy-8-quinolein. At a concentration of chlorquinaldol of 0.1~0.2%(W/V), neisseria gonorrhoeae and Chlamydia trachomatis decreased by approximately 10chlorquinaldol after 60 min. |
5,7-dichloro-2-methylquinolin-8-ol - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | VC5600000 |
5,7-dichloro-2-methylquinolin-8-ol - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| effect | , increased leucorrhea from any cause. Broad spectrum of antibacterial, Candida albicans, vaginal DM, vaginal Gardner bacteria, Escherichia coli, Streptococcus, Staphylococcus aureus, Enterococcus, common Proteus are effective, can quickly eliminate infection. Baojing can not only enhance the role of vaginal local resistance, and can effectively kill pathogenic bacteria. 1 tablet daily for 18 consecutive days. The already moistened tablet is placed in the deep part of the vagina and it is recommended to apply the drug in the evening. Route of administration: Vaginal administration. Like all drugs, this product can cause adverse reactions in some patients, with occasional irritation, itching, and allergic reactions. The chloroquinadin/promestrene vaginal tablets have a different mechanism of action, and are a combination of broad spectrum bacteriostatic agents and vaginal mucosal protective agents. Its role has their own obvious characteristics, and will not produce interaction. The mechanism of action of chloroquinandol in the prescription is: chloroquinandol is a yellow needle-like crystal with a slightly irritating odor. As early as the 50's, many pharmaceutical companies in Europe have conducted extensive research and found that it has anti-fungal, trichomonas, bacteria (G and G-), raw materials and Mycoplasma and other antimicrobial pathogens, is a broad-spectrum bacteriostatic agent. Because it is slightly soluble in water, pathogen microorganisms generally enter the pathogen cells through endocytosis, so that the pH value of the pathogen cells changes and the metabolism of the pathogen is inhibited, which eventually leads to the death of the pathogen, human epithelial cells have no phagocytic function for chloroquinandol, so the drug has little adverse reaction to human body when used in vitro.|
| biological activity | Chlorquinaldol is an antimicrobial agent. |
Last Update：2024-04-09 02:00:11
Supplier List
Spot supply
Product Name: Chloroquine Impurity 4 Visit Supplier Webpage Request for quotationCAS: 72-80-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 5,7-Dichloro-2-Methyl-8-Quinolinol Visit Supplier Webpage Request for quotationCAS: 72-80-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Chloroquine Impurity 4 Visit Supplier Webpage Request for quotationCAS: 72-80-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 5,7-Dichloro-2-Methyl-8-Quinolinol Visit Supplier Webpage Request for quotationCAS: 72-80-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History