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5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Molecular Formula: C16H13FN2O3

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  5. 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl... - Names and Identifiers

Name 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Synonyms Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...
(Z)-5-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxylic Acid
(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic acid
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
(3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-on
(3Z)-3-[(3,5-DiMethyl-4-carboxy-1H-pyrrol-2-yl)Methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one
5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
1H-Pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-
1H-pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-
CAS 356068-93-4
EINECS 1592732-453-0
InChI InChI=1/C16H13FN2O3/c1-7-13(18-8(2)14(7)16(21)22)6-11-10-5-9(17)3-4-12(10)19-15(11)20/h3-6,18H,1-2H3,(H,19,20)(H,21,22)/b11-6-

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl... - Physico-chemical Properties

Molecular FormulaC16H13FN2O3
Molar Mass300.28
Density1.454±0.06 g/cm3(Predicted)
Melting Point320 °C (decomp)
Boling Point588.4±50.0 °C(Predicted)
Flash Point309.683°C
Solubility Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
Vapor Presure0mmHg at 25°C
AppearanceSolid
ColorDark Orange
pKa5.79±0.50(Predicted)
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.69
UseThis product is for scientific research only and shall not be used for other purposes.

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl... - Introduction

5-((Z)-(-) methyl)-2,-acid is an organic compound with the following properties:

1. appearance: solid or powder substance.
2. molecular formula: C15H12FN3O3.
3. Molecular weight: 305.27g/mol.
4. Solubility: Slightly soluble in water, soluble in organic solvents such as dimethyl sulfoxide, methanol and ethanol.
5. melting point: about 180-182 ℃.

The main uses of this compound include:
1. pharmaceutical field: can be used for the synthesis of various drugs, such as anti-inflammatory drugs and anti-tumor drugs.
2. chemical research: can be used as an important intermediate in organic synthesis.

Preparation Method:
The compound can usually be prepared by the following steps:
1. 2,4-dimethyl-1H-pyrrole-3-carboxylic acid is reacted with an appropriate aryl quaternary ammonium salt under basic conditions to obtain an N-aryl substrate.
2. the N-aryl substrate and 5-fluoro -2-oxo-indolane reaction to generate the target product.

Safety Information:
1. This compound should follow chemical safety procedures during handling and storage, and avoid contact with skin, eyes and clothing.
2. Avoid inhaling dust from compounds and operate in a well-ventilated environment.
3. If contact occurs, immediately flush the affected area with plenty of water and seek medical assistance.
4. The compound may be harmful to the environment, and the waste should be properly disposed of in accordance with relevant regulations.
Last Update:2024-04-09 02:00:45
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...
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Spot supply
Product Name: (Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Visit Supplier Webpage Request for quotation
CAS: 356068-93-4
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Mobile: +86-18621343501
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Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: (Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Visit Supplier Webpage Request for quotation
CAS: 356068-93-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid Visit Supplier Webpage Request for quotation
CAS: 356068-93-4
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View History
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