5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazin-3-yl)phenol
LMI070
CAS: 1562338-42-4
Molecular Formula: C22H27N5O2
5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazin-3-yl)phenol - Names and Identifiers
5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazin-3-yl)phenol - Physico-chemical Properties
| Molecular Formula | C22H27N5O2 |
| Molar Mass | 393.48 |
| Density | 1.171±0.06 g/cm3(Predicted) |
| Boling Point | 660.0±55.0 °C(Predicted) |
| Solubility | DMSO: 6.12 mg/mL |
| pKa | 7.84±0.40(Predicted) |
| Storage Condition | -20℃ |
5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazin-3-yl)phenol - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.541 ml | 12.707 ml | 25.414 ml |
| 5 mM | 0.508 ml | 2.541 ml | 5.083 ml |
| 10 mM | 0.254 ml | 1.271 ml | 2.541 ml |
| 5 mM | 0.051 ml | 0.254 ml | 0.508 ml |
Last Update：2024-01-02 23:10:35
5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazin-3-yl)phenol - Reference Information
| biological activity | Branaplam (LMI070) is a highly selective survival motor neuron-2 (SMN2) splicing regulator, the EC50 was 0.02 μm. |
| Target | Value |
| SMN2 () | 0.02 μM(EC50) |
Last Update：2024-04-09 21:04:16
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Product Name: LMI070 Visit Supplier Webpage Request for quotationCAS: 1562338-42-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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