5-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1-methyl-2,4(1H,3H)-pyrimidinedione
PSEUDOTHYMIDINE
CAS: 65358-15-8
Molecular Formula: C10H14N2O5
5-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1-methyl-2,4(1H,3H)-pyrimidinedione - Names and Identifiers
5-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1-methyl-2,4(1H,3H)-pyrimidinedione - Physico-chemical Properties
| Molecular Formula | C10H14N2O5 |
| Molar Mass | 242.23 |
| Density | 1.452±0.06 g/cm3(Predicted) |
| pKa | 9.43±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | Pseudothymidine is a C-nucleoside analog of thymidine. The calculated ΔΔG° 50 /mod is -0.5 kcal/mol, with a Δ T m /mod of 0.82°C. For the duplexes containing nine dA-T/ψT pairs, the Δ T m /mod is -0.9°C and a ΔΔG° 50 /mod is +1.1 kcal/mol. The modification of the duplex containing 12 consecutive dA-T/ψT base pairs produces a Δ T m /mod of -0.9°C and a ΔΔG° 50 /mod of +1.2 kcal/mol. |
5-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1-methyl-2,4(1H,3H)-pyrimidinedione - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.128 ml | 20.642 ml | 41.283 ml |
| 5 mM | 0.826 ml | 4.128 ml | 8.257 ml |
| 10 mM | 0.413 ml | 2.064 ml | 4.128 ml |
| 5 mM | 0.083 ml | 0.413 ml | 0.826 ml |
Last Update：2024-01-02 23:10:35
5-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1-methyl-2,4(1H,3H)-pyrimidinedione - Reference Information
| biological activity | pseudo midine is a C- nucleoside (C-nucleosid) analog of thymidine. |
Last Update：2024-04-09 21:54:55
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