5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde

5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde - Names and Identifiers

Name	5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde
Synonyms	5-(4-Hydroxypiperidino)-2-Thio 5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde 5-(4-Hydroxypiperidino)thiophene-2-carboxaldehyde 5-(4-Hydroxypiperidin-1-yl)thiophene-2-carbaldehyde 5-(4-hydroxypiperidin-1-yl)thiophene-2-carbaldehyde 5-(4-Hydroxy-1-piperidinyl)-2-thiophenecarbaldehyde 5-(4-Hydroxy-1-piperidinyl)-2-thiophenecarboxaldehyde 2-Thiophenecarboxaldehyde, 5-(4-hydroxy-1-piperidinyl)- 2-thiophenecarboxaldehyde, 5-(4-hydroxy-1-piperidinyl)- 2-Formyl-5-(4-hydroxypiperidin-1-yl)thiophene, 1-(5-Formylthien-2-yl)-4-hydroxypiperidine
CAS	207290-72-0
InChI	InChI=1/C10H13NO2S/c12-7-9-1-2-10(14-9)11-5-3-8(13)4-6-11/h1-2,7-8,13H,3-6H2

5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde - Physico-chemical Properties

Molecular Formula	C10H13NO2S
Molar Mass	211.28
Density	1.321±0.06 g/cm3(Predicted)
Melting Point	137-139°
Boling Point	417.8±45.0 °C(Predicted)
Flash Point	206.5°C
Vapor Presure	9.97E-08mmHg at 25°C
Maximum wavelength(λmax)	371nm(MeOH)(lit.)
pKa	14.77±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.642

5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde - Risk and Safety

Hazard Class

IRRITANT

5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde - Introduction

5-(4-Hydroxypiperidino)-2-thiophenecarbaldehyde, also known as hydroxypiperaldehyde, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Molecular formula: C11H9NO2S
-Appearance: White to light yellow crystalline solid
-Melting Point: about 174-178 ℃
-Solubility: Soluble in a variety of organic solvents, such as ethanol and dimethyl sulfoxide

Use:
-Hydroxypiperaldehyde is an important organic synthesis intermediate, usually used in the synthesis of other organic compounds.
-It is widely used as a synthetic raw material for antiviral drugs and anticancer drugs in the pharmaceutical field.

Method:
Hydroxypiperaldehyde can be synthesized by the following methods:
1. 4-hydroxypiperidine reacts with 2-thiophenecarboxaldehyde under alkaline conditions to generate the target product.
2. Through different synthetic pathways, such as reduction, oxidation, acylation and other chemical reactions, can be obtained.

Safety Information:
-Hydroxypiperaldehyde is irritating to the skin, eyes and respiratory tract, please be careful to avoid contact.
-During operation, please wear appropriate protective equipment, such as lab gloves, safety glasses and masks.
-When storing and handling, please follow the correct dangerous goods practice and keep it properly.
-Under no circumstances should hydroxypiperaldehyde be exposed to flames or high temperatures to avoid harmful substances or fires.

Please note that this is only a description of a common situation of hydroxypiperaldehyde. Please conduct sufficient research and experimental verification before specific application. Use in chemical experiments or industrial processes must follow the relevant safety procedures.

Last Update：2024-04-09 15:17:55