5-(Benzyloxy)-2-(1-piperazinyl)pyrimidine

5-(Benzyloxy)-2-(1-piperazinyl)pyrimidine - Names and Identifiers

Name	5-(benzyloxy)-2-piperazinopyrimidine
Synonyms	5-(benzyloxy)-2-piperazinopyrimidine 5-Benzyloxy-2-(1-piperazinyl)pyriMidine 5-(Benzyloxy)-2-(1-piperazinyl)pyrimidine 5-(Benzyloxy)-2-(piperazin-1-yl)pyriMidine 5-(PhenylMethoxy)-2-(1-piperazinyl)-pyriMidine Pyrimidine, 5-(phenylmethoxy)-2-(1-piperazinyl)-
CAS	87789-61-5
InChI	InChI=1S/C15H18N4O/c1-2-4-13(5-3-1)12-20-14-10-17-15(18-11-14)19-8-6-16-7-9-19/h1-5,10-11,16H,6-9,12H2

5-(Benzyloxy)-2-(1-piperazinyl)pyrimidine - Physico-chemical Properties

Molecular Formula	C15 H18 N4 O
Molar Mass	270.33
Density	1.181±0.06 g/cm3(Predicted)
Melting Point	95-96 °C
Boling Point	469.8±55.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White
pKa	8.57±0.10(Predicted)
Storage Condition	2-8°C

5-(Benzyloxy)-2-(1-piperazinyl)pyrimidine - Introduction

5-(benzyloxy)-2-piperazinopyrimidine is an organic compound with a molecular formula of C16H17N5O and a molecular weight of 295.34. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 5-(benzyloxy)-2-piperazinopyrimidine is a white solid.
-melting point: about 190-192 ℃.
-Solubility: Soluble in non-polar organic solvents such as ether, chloroform and dichloromethane, insoluble in water.

Use:
- 5-(benzyloxy)-2-piperazinopyrimidine is an important organic synthesis intermediate, which is widely used in the pharmaceutical industry.
-It can be used as a drug raw material for the synthesis of antiepileptic drugs, antipsychotic drugs and other nervous system related drugs.

Preparation Method:
The preparation method of -5-(benzyloxy)-2-piperazinopyrimidine is usually carried out by chemical synthesis.
-A commonly used preparation method is to react 2-(1-piperazinyl) pyrimidine with benzyl bromide to produce 5-(benzyloxy)-2-piperazinopyrimidine.

Safety Information:
- 5-(benzyloxy)-2-piperazinopyrimidine is less toxic and dangerous, but as a chemical, it still needs to be handled with care.
-Use in accordance with laboratory practices and avoid contact with skin and eyes.
-Avoid inhaling dust or gas and maintain a well-ventilated working environment.
-Store in a cool and dry place, away from fire and flammable materials.

Please note that the above information is for reference only, and the specific operation and use should be carried out according to specific requirements.

Last Update：2024-04-09 15:18:00