5-(Chloroacetyl)-1H-indole

5-(Chloroacetyl)-1H-indole - Names and Identifiers

Name	Ketone, chloromethyl indol-5-yl (6CI)
Synonyms	5-(Chloroacetyl)-1H-indole Ketone, chloroMethyl indol-5-yl Ketone, chloromethyl indol-5-yl 2-chloro-1-(1H-indol-5-yl)ethanone 2-Chloro-1-(1h-indol-5-yl)ethan-1-one Ketone, chloromethyl indol-5-yl (6CI) Ethanone, 2-chloro-1-(1H-indol-5-yl)- 2-Chloro-1-(1H-indol-5-yl)ethan-1-one, 5-(2-Chloroethanoyl)-1H-indole
CAS	103028-56-4

5-(Chloroacetyl)-1H-indole - Physico-chemical Properties

Molecular Formula	C10H8ClNO
Molar Mass	193.63
Density	1.337±0.06 g/cm3(Predicted)
Boling Point	379.1±17.0 °C(Predicted)
pKa	15.89±0.30(Predicted)
Storage Condition	2-8°C

5-(Chloroacetyl)-1H-indole - Introduction

Indol-5-yl chloromethyl ketone is an organic compound with the chemical formula C10H8ClNO. The following is a description of the properties, uses, preparation and safety information of indole -5-yl chloromethyl ketone:

Nature:
Indole -5-yl chloromethyl ketone is a colorless to pale yellow solid. It is stable at room temperature and soluble in some organic solvents, such as ethanol and dimethyl sulfoxide. It has some toxicity.

Use:
Indole -5-yl chloromethyl ketone is commonly used as a reagent in organic synthesis, especially as a cytochrome P450 mimic enzyme in quaternary ammonium salt reaction. It can also be used as a pharmaceutical intermediate for the synthesis of indole compounds and bioactive molecules.

Preparation Method:
The preparation method of indole -5-yl chloromethyl ketone can be obtained by reacting indole with chloroformyl chloride. Specific synthetic steps can refer to the organic chemical synthesis handbook or related literature.

Safety Information:
Indole -5-yl chloromethyl ketone should be handled in accordance with general laboratory safety procedures. Due to its toxicity, it should be handled with care and avoid inhalation, swallowing and skin contact. Wear appropriate protective equipment, such as safety glasses, lab gloves and lab coats, if necessary. When using or storing indole -5-yl chloromethyl ketone, please follow the relevant safety data sheet for the chemical.

Last Update：2024-04-09 21:04:16