5-(Hydroxymethyl)thiazol-2-ylamine - Names and Identifiers
Name | 2-Amino-5-thiazolemethanol
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Synonyms | 2-Amino-5-thiazolemethanol 5-Thiazolemethanol, 2-amino 5-Thiazolemethanol, 2-amino- (2-AMinothiazol-5-yl)Methanol (2-amino-5-thiazolyl)methanol 5-Thiazolemethanol,2-amino-(9CI) 2-Amino-5-(hydroxymethyl)thiazole 5-(Hydroxymethyl)thiazol-2-ylamine (2-Amino-1,3-thiazol-5-yl)methanol 2-Amino-5-(hydroxymethyl)-1,3-thiazole (2-AMinothiazol-5-yl)Methanol hydrochloride (2-amino-1,3-thiazol-5-yl)methanol hydrochloride
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CAS | 131184-73-1
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InChI | InChI=1/C4H6N2OS/c5-4-6-1-3(2-7)8-4/h1,7H,2H2,(H2,5,6) |
5-(Hydroxymethyl)thiazol-2-ylamine - Physico-chemical Properties
Molecular Formula | C4H6N2OS
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Molar Mass | 130.17 |
Density | 1.475 |
Boling Point | 340.7±17.0 °C(Predicted) |
Flash Point | 159.873°C |
Solubility | Dichloromethane, Methanol |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | Yellow |
pKa | 13.54±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.682 |
5-(Hydroxymethyl)thiazol-2-ylamine - Introduction
2-Amino-5-thiazolecinol is an organic compound whose chemical formula is C4H5N3OS. The following is an introduction to its nature, use, preparation and safety information:
Nature:
2-Amino-5-thiazole methanol is a solid with the appearance of colorless or white crystals. It is soluble in water and alcohol solvents at room temperature. The compound has a neutral pH and is less volatile.
Use:
2-Amino-5-thiazole methanol has important applications in the pharmaceutical and pesticide industries. It can be used as an intermediate in the synthesis of certain drugs and pesticides. In addition, it can also be used in certain reagents in analytical chemistry, as well as as synthetic raw materials for vitamins, biologically active substances and cationic dyes.
Preparation Method:
A commonly used method for preparing 2-amino -5-thiazole methanol is obtained by the reaction of aqueous ammonia and 2-mercaptoethanol in a steric polar solvent. The reaction is generally carried out under neutral or basic conditions, and the reaction temperature and reaction time can be adjusted according to the specific conditions.
Safety Information:
There is limited safety data on 2-amino-5-thiazolemethanol. As a chemical, the use of the process should comply with the relevant safety procedures. During operation, appropriate protective equipment, such as lab gloves and goggles, should be worn to avoid contact with skin and eyes. During storage and transportation, it should be sealed and kept away from open flames and high temperatures. If you accidentally touch or eat, you should seek medical help immediately.
Last Update:2024-04-09 21:54:55