5-(Methoxycarbonyl)-2-Pyridine

5-(Methoxycarbonyl)-2-Pyridine - Names and Identifiers

Name	5-(Methoxycarbonyl)pyridine-2-carboxylic acid
Synonyms	BUTTPARK 4357-32 5-(Methoxycarbonyl)-2-Pyridine 5-(Methoxycarbonyl)picolinic acid 5-methoxycarbonyl-2-pyridinecarboxylate 5-(methoxycarbonyl)pyridine-2-carboxylate 5-(Methoxycarbonyl)pyridine-2-carboxyic acid Pyridine-2,5-dicarboxylic acid 5-methyl ester 5-(METHOXYCARBONYL)PYRIDINE-2-CARBOXYLIC ACID 5-(METHOXYCARBONYL)-2-PYRIDINECARBOXYLIC ACID 5-(Methoxycarbonyl)pyridine-2-carboxylic acid
CAS	17874-79-2
InChI	InChI=1/C8H7NO4/c1-13-8(12)5-2-3-6(7(10)11)9-4-5/h2-4H,1H3,(H,10,11)/p-1

5-(Methoxycarbonyl)-2-Pyridine - Physico-chemical Properties

Molecular Formula	C8H7NO4
Molar Mass	181.15
Density	1.361±0.06 g/cm3(Predicted)
Melting Point	187 °C
Boling Point	347.9±27.0 °C(Predicted)
Flash Point	164.2°C
Solubility	Chloroform (Sparingly, Heated), DMSO (Slightly), Methanol (Slightly)
Vapor Presure	1.97E-05mmHg at 25°C
Appearance	Crystallization
Color	White to Off-White
pKa	3.21±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Stability	Hygroscopic
MDL	MFCD00179343

5-(Methoxycarbonyl)-2-Pyridine - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust.
HS Code	29333990
Hazard Class	IRRITANT

5-(Methoxycarbonyl)-2-Pyridine - Introduction

5-(methoxy carbonyl)pyridine-2-carboxylic acid, also known as methoxycarbonylpyridine-2-carboxylic acid, is an organic compound. It has the chemical formula cmember hhsno, and a molecular weight of 181.15g/mol.

Nature:
5-(Methoxycarbonyl)pyridine-2-carboxylic acid is a white crystalline solid that can be dissolved in polar solvents such as water and alcohols. It has strong acidity and electrophilicity.

Use:
5-(Methoxycarbonyl)pyridine-2-carboxylic acid has a wide range of applications in organic synthesis. It can be used as a carbon acylation reagent and acylation reagent, and plays an important role in the synthesis of ketones and esters. In addition, it can also be used as a pharmaceutical intermediate and pesticide intermediate synthesis.

Method:
5-(Methoxycarbonyl)pyridine-2-carboxylic acid is synthesized by various methods. A common synthetic method is the reaction of 2-pyridinecarboxaldehyde with Formic Anhydride under basic conditions to produce the target product.

Safety Information:
5-(Methoxycarbonyl)pyridine-2-carboxylic acid is an organic compound. Generally speaking, it has a certain chemical reactivity. Attention should be paid to its safety during operation and avoid contact with skin and eyes. In the experiment or industrial production, the concentration and dosage should be reasonably controlled, and the relevant operating procedures and safety operation guidelines should be followed. Wear appropriate protective equipment, such as gloves, glasses and lab clothes, if necessary.

Last Update：2024-04-09 02:00:43