5-(Trifluoromethoxy)indoline-2,3-dione
5-(trifluoromethoxy)isatin
CAS: 169037-23-4
Molecular Formula: C9H4F3NO3
5-(Trifluoromethoxy)indoline-2,3-dione - Names and Identifiers
5-(Trifluoromethoxy)indoline-2,3-dione - Physico-chemical Properties
| Molecular Formula | C9H4F3NO3 |
| Molar Mass | 231.13 |
| Density | 1.562±0.06 g/cm3(Predicted) |
| Melting Point | 170-172°C(lit.) |
| Water Solubility | Insoluble in water. |
| Appearance | Solid |
| pKa | 8.49±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| MDL | MFCD00192524 |
| Use | Usually used as reactant for preparation of (fluorinated-indolinonylidene)-hydrazine-carbothioamides by condensation with thiosemicarbazides,oxindole derivatives as TAk1 kinase inhibitors,isatin thiosemicarbazones via condensation with thiosemicarbaz |
5-(Trifluoromethoxy)indoline-2,3-dione - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Note | Irritant/Keep Cold |
5-(Trifluoromethoxy)indoline-2,3-dione - Introduction
5-(trifluoromethoxy)isatin is an organic pigment with the chemical name 5-(trifluoromethoxy)-4,4 '-dinitro-2, 2'-dinitro-3, 3 '-dichlorodiphenylamine. Its chemical formula is C16H10Cl2F3N5O6.
Nature:
1. Appearance: 5-(trifluoromethoxy)isatin is a red crystalline powder.
2. Stability: It is stable to light, heat and chemistry, and has good weather resistance.
3. Solubility: It has a certain degree of solubility in solvents, soluble in high boiling point solvents such as dimethylformamide (DMF) and dimethylsulfamide (DMSO).
Use:
1. Pigment: 5-(trifluoromethoxy)isatin is widely used as a red pigment and can be used in paints, coatings, plastics, rubber and printing inks.
2. Labeling agents: Due to its high absorption and emission capabilities in the visible region, 5-(trifluoromethoxy)isatin can also be used as a biomarker and dye, such as cell staining, protein analysis, etc.
Method: The preparation method of
5-(trifluoromethoxy)isatin is more complicated and is usually obtained through several steps of reaction between synthetic raw materials. Specific synthetic methods include nitration, amination, chlorination and substitution reactions.
Safety Information:
1. 5-(trifluoromethoxy)isatin is not harmful to human body under normal use conditions, but inhalation of dust and contact with skin or eyes should be avoided to prevent allergy or irritation.
2. In the process of handling and use, should take appropriate protective measures, such as wearing gloves, respiratory protective equipment and safety glasses. If you accidentally touch or take it by mistake, you should seek medical attention immediately.
Nature:
1. Appearance: 5-(trifluoromethoxy)isatin is a red crystalline powder.
2. Stability: It is stable to light, heat and chemistry, and has good weather resistance.
3. Solubility: It has a certain degree of solubility in solvents, soluble in high boiling point solvents such as dimethylformamide (DMF) and dimethylsulfamide (DMSO).
Use:
1. Pigment: 5-(trifluoromethoxy)isatin is widely used as a red pigment and can be used in paints, coatings, plastics, rubber and printing inks.
2. Labeling agents: Due to its high absorption and emission capabilities in the visible region, 5-(trifluoromethoxy)isatin can also be used as a biomarker and dye, such as cell staining, protein analysis, etc.
Method: The preparation method of
5-(trifluoromethoxy)isatin is more complicated and is usually obtained through several steps of reaction between synthetic raw materials. Specific synthetic methods include nitration, amination, chlorination and substitution reactions.
Safety Information:
1. 5-(trifluoromethoxy)isatin is not harmful to human body under normal use conditions, but inhalation of dust and contact with skin or eyes should be avoided to prevent allergy or irritation.
2. In the process of handling and use, should take appropriate protective measures, such as wearing gloves, respiratory protective equipment and safety glasses. If you accidentally touch or take it by mistake, you should seek medical attention immediately.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: 5-(trifluoromethoxy)isatin Visit Supplier Webpage Request for quotationCAS: 169037-23-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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