5-(bromomethyl)-2-(trifluoromethyl)pyridine

5-(bromomethyl)-2-(trifluoromethyl)pyridine - Names and Identifiers

Name	5-(bromomethyl)-2-(trifluoromethyl)pyridine
Synonyms	LogP 3-Bromomethyl-6-(trifluoromethyl)pyridine 5-(Bromomethyl)-2-trifluoromethyl)pyridine 5-(Bromomethyl)-2-(trifluoromethyl)pyridine 5-(bromomethyl)-2-(trifluoromethyl)pyridine pyridine, 5-(bromomethyl)-2-(trifluoromethyl)- PYRIDINE, 5-(BROMOMETHYL)-2-(TRIFLUOROMETHYL)-
CAS	108274-33-5
InChI	InChI=1/C7H5BrF3N/c8-3-5-1-2-6(12-4-5)7(9,10)11/h1-2,4H,3H2

5-(bromomethyl)-2-(trifluoromethyl)pyridine - Physico-chemical Properties

Molecular Formula	C7H5BrF3N
Molar Mass	240.02
Density	1.647
Boling Point	218.4±35.0 °C(Predicted)
Flash Point	85.9°C
Vapor Presure	0.186mmHg at 25°C
pKa	-0.35±0.22(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.488

5-(bromomethyl)-2-(trifluoromethyl)pyridine - Introduction

5-Bromomethyl-2-trifluoromethylpyridine is an organic compound with the chemical formula C7H4BrF3N. It is a colorless liquid with a low boiling point and melting point. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: colorless liquid
-Molecular weight: 229.01g/mol
-Boiling Point: 87-89°C
-Melting point:-14°C
-Solubility: Soluble in some organic solvents, such as alcohol, ether, etc.
-flammability: has a certain flammability

Use:
5-Bromomethyl-2-trifluoromethylpyridine has a variety of uses in organic synthesis, commonly used in the following areas:
-Function as a reagent and catalyst in chemical reactions
-Used as an intermediate in the synthesis of other organic compounds
-for the preparation of drugs, pesticides and other organic synthetic compounds

Preparation Method:
5-Bromomethyl-2-trifluoromethylpyridine can be synthesized by the following steps:
1.3-bromopyridine reacts with fluorinated hydrazine to generate 3-bromopyridine -2-hydrazide
2. 3-bromopyridine-2-hydrazide reacts with trifluoromethyl compound to generate 5-bromomethyl-2-trifluoromethylpyridine

Safety Information:
-5-Bromomethyl-2-trifluoromethylpyridine is irritating, and contact with skin and eyes may cause irritation and pain.
-Avoid inhaling its vapors or sprays.
-Wear protective gloves, goggles and protective clothing when using.
-Keep away from open flames and high temperatures during use and storage.
-In case of contact or misuse, rinse immediately with water and seek medical help.

Last Update：2024-04-09 15:17:50