5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole - Names and Identifiers

Name	5-Indoleboronic acid pinacol ester
Synonyms	Indolyl-5-boronic acid pi... 5-Indoleboronic acid pinacol ester Indole-5-boronic acid pinacol ester Indolyl-5-boronic acid pinacol ester 1H-indol-5-ylboronic acid pinacol ester 5-Indolylboronic acid, pinacol cyclic ester 5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1h- indole (5-Indoleboronic acid pinacol ester) 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole, 2-(1H-Indol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS	269410-24-4
InChI	InChI=1/C14H18BNO2/c1-13(2)14(3,4)18-15(17-13)11-5-6-12-10(9-11)7-8-16-12/h5-9,16H,1-4H3

5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole - Physico-chemical Properties

Molecular Formula	C14H18BNO2
Molar Mass	243.11
Density	1.11±0.1 g/cm3(Predicted)
Melting Point	120-125 °C (lit.)
Boling Point	396.0±15.0 °C(Predicted)
Flash Point	193.3°C
Water Solubility	Insoluble
Vapor Presure	4.03E-06mmHg at 25°C
Appearance	Crystalline Powder
Color	Pale yellow to brown
pKa	17.01±0.30(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.562
MDL	MFCD03789263

5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
HS Code	29349990
Hazard Note	Irritant

5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indole - Introduction

5-Indoleboronic acid pinacol ester is an organic compound with the chemical formula C14H19BNO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 58 ° C
-Solubility: Soluble in some organic solvents, such as chloroform and dimethylformamide
-Stability: stable under dry conditions, but hydrolysis may occur in a humid environment

Use:
- 5-Indoleboronic acid pinacol ester is an important organic synthesis intermediate, which is widely used in organic chemical synthesis.
-It can be used as a reagent for the synthesis of ketone carbonyl compounds, a catalyst for organic chemical reactions, and a raw material for the synthesis of indole compounds.

Method:
- 5-Indoleboronic acid pinacol ester can be prepared by transesterification reaction between pinacol and 5-indole boronic acid.

Safety Information:
- 5-Indoleboronic acid pinacol ester has no obvious safety hazard under regular operation.
-Because it is a chemical, it is still necessary to take appropriate safety measures when handling, such as wearing personal protective equipment (such as gloves, safety glasses) and operating in a well-ventilated area, avoid inhalation or contact with skin.
-When handling and storing, keep away from ignition and oxidizing agents, and avoid contact with air, humid conditions and water.

Last Update：2024-04-10 22:29:15