5-AMINO-1-BOC-BENZOIMIDAZOLE
5-Amino-1-Boc-Benzoimidazole
CAS: 297756-31-1
Molecular Formula: C12H15N3O2
5-AMINO-1-BOC-BENZOIMIDAZOLE - Names and Identifiers
5-AMINO-1-BOC-BENZOIMIDAZOLE - Physico-chemical Properties
| Molecular Formula | C12H15N3O2 |
| Molar Mass | 233.27 |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
5-AMINO-1-BOC-BENZOIMIDAZOLE - Introduction
It is a compound commonly used in the field of organic synthesis. Its Properties, Uses, preparation methods and safety information are as follows:
Nature:
is a white solid with the molecular formula C12H15N3O2 and a relative molecular mass of 233.27g/mol. It has a melting point of about 165-170 ° C. And is soluble in some organic solvents such as dimethyl sulfoxide and acetonitrile.
Use:
is widely used in organic synthesis of substrates and intermediates. It is commonly used in the synthesis of many bioactive molecules, such as drugs, pesticides and dyes. Because of its unique structure, it can be modified by a series of chemical reactions to obtain compounds with specific chemical activity.
Method: The preparation method of
is generally to introduce a protecting group (the protecting group is usually Boc Group) on the nitrogen of benzimidazole. The specific steps are as follows:
1. In an appropriate solvent, benzimidazole is reacted with tributyl methacrylate to generate N-Boc-benzimidazole.
2. Under mild conditions, remove the protecting group from the resulting N-Boc-benzimidazole by acid hydrolysis to obtain the pyridine.
Safety Information:
There is no obvious harm to human health under general operating conditions, but any chemical should be used with caution. Therefore, it is necessary to wear appropriate personal protective equipment, such as protective glasses and gloves, when using to avoid inhalation of gases, dust and liquids. In addition, it should be operated under well-ventilated laboratory conditions, avoiding contact with fire and oxidizing agents. If the skin is touched or inhaled into the respiratory tract, immediately wash or seek medical assistance. Be sure to store this compound out of reach of children. For detailed safety information and hazard assessment, refer to the relevant safety literature.
Nature:
is a white solid with the molecular formula C12H15N3O2 and a relative molecular mass of 233.27g/mol. It has a melting point of about 165-170 ° C. And is soluble in some organic solvents such as dimethyl sulfoxide and acetonitrile.
Use:
is widely used in organic synthesis of substrates and intermediates. It is commonly used in the synthesis of many bioactive molecules, such as drugs, pesticides and dyes. Because of its unique structure, it can be modified by a series of chemical reactions to obtain compounds with specific chemical activity.
Method: The preparation method of
is generally to introduce a protecting group (the protecting group is usually Boc Group) on the nitrogen of benzimidazole. The specific steps are as follows:
1. In an appropriate solvent, benzimidazole is reacted with tributyl methacrylate to generate N-Boc-benzimidazole.
2. Under mild conditions, remove the protecting group from the resulting N-Boc-benzimidazole by acid hydrolysis to obtain the pyridine.
Safety Information:
There is no obvious harm to human health under general operating conditions, but any chemical should be used with caution. Therefore, it is necessary to wear appropriate personal protective equipment, such as protective glasses and gloves, when using to avoid inhalation of gases, dust and liquids. In addition, it should be operated under well-ventilated laboratory conditions, avoiding contact with fire and oxidizing agents. If the skin is touched or inhaled into the respiratory tract, immediately wash or seek medical assistance. Be sure to store this compound out of reach of children. For detailed safety information and hazard assessment, refer to the relevant safety literature.
Last Update：2024-04-09 21:04:16
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Product Name: 5-AMINO-1-BOC-BENZOIMIDAZOLE Visit Supplier Webpage Request for quotation
CAS: 297756-31-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 297756-31-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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