5-Amino-2-chloroanisole
4-Chloro-3-methoxyaniline
CAS: 13726-14-2
Molecular Formula: C7H8ClNO
5-Amino-2-chloroanisole - Names and Identifiers
5-Amino-2-chloroanisole - Physico-chemical Properties
| Molecular Formula | C7H8ClNO |
| Molar Mass | 157.6 |
| Density | 1.234±0.06 g/cm3(Predicted) |
| Melting Point | 77-79 |
| Boling Point | 274.1±20.0 °C(Predicted) |
| Flash Point | 119.546°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.006mmHg at 25°C |
| Appearance | Solid |
| Color | Pale Yellow to Pale Brown |
| pKa | 3.54±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.573 |
5-Amino-2-chloroanisole - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN2233 |
| HS Code | 29214200 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
5-Amino-2-chloroanisole - Introduction
3-methoxy-4-chloroaniline is an organic compound with the molecular formula C7H8ClNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless or yellowish crystal
-Solubility: Soluble in ethanol, chloroform and dichloromethane, insoluble in water
-Melting point: approximately between 40-45 ℃
-Boiling point: about 200-210 ℃
Use:
-3-methoxy-4-chloroaniline is widely used in organic synthesis, commonly used as dyes, pesticides and pharmaceutical intermediates.
-It can be used to prepare other organic compounds, such as dyes, fragrances and medicines.
Preparation Method:
-3-methoxy-4-chloroaniline can be prepared by reacting p-nitrobenzene with methyl chloride and reducing to produce nitroaniline, then reacting it with methanol to produce 3-nitro-4-methoxyaniline, then reducing it with zinc-hydrochloric acid, and finally producing 3-methoxy-4-chloroaniline by oxidizing hydrogen chloride.
Safety Information:
-3-methoxy-4-chloroaniline is an organic compound with certain toxicity. Contact with skin, eyes or inhalation of high concentrations of gas may cause irritation and injury, and attention should be paid to the use of personal protective equipment.
-It is recommended to use it in a well-ventilated place and avoid inhaling its vapor or dust.
-It should be stored in a dry, cool and ventilated place, away from fire and oxidizing agents, and avoid contact with oxygen or strong acid.
-During use and handling, please strictly follow the safety operation procedures and follow relevant regulations and guidelines.
Nature:
-Appearance: colorless or yellowish crystal
-Solubility: Soluble in ethanol, chloroform and dichloromethane, insoluble in water
-Melting point: approximately between 40-45 ℃
-Boiling point: about 200-210 ℃
Use:
-3-methoxy-4-chloroaniline is widely used in organic synthesis, commonly used as dyes, pesticides and pharmaceutical intermediates.
-It can be used to prepare other organic compounds, such as dyes, fragrances and medicines.
Preparation Method:
-3-methoxy-4-chloroaniline can be prepared by reacting p-nitrobenzene with methyl chloride and reducing to produce nitroaniline, then reacting it with methanol to produce 3-nitro-4-methoxyaniline, then reducing it with zinc-hydrochloric acid, and finally producing 3-methoxy-4-chloroaniline by oxidizing hydrogen chloride.
Safety Information:
-3-methoxy-4-chloroaniline is an organic compound with certain toxicity. Contact with skin, eyes or inhalation of high concentrations of gas may cause irritation and injury, and attention should be paid to the use of personal protective equipment.
-It is recommended to use it in a well-ventilated place and avoid inhaling its vapor or dust.
-It should be stored in a dry, cool and ventilated place, away from fire and oxidizing agents, and avoid contact with oxygen or strong acid.
-During use and handling, please strictly follow the safety operation procedures and follow relevant regulations and guidelines.
Last Update：2024-04-09 15:17:52
