5-Amino-4-methylpyrimidine - Names and Identifiers
5-Amino-4-methylpyrimidine - Physico-chemical Properties
Molecular Formula | C5H7N3
|
Molar Mass | 109.13 |
Density | 1.155±0.06 g/cm3(Predicted) |
Melting Point | 151-151.5 °C |
Boling Point | 246.8±20.0 °C(Predicted) |
pKa | 3.21±0.16(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
5-Amino-4-methylpyrimidine - Introduction
5-Amino-4-methylpyrimidine is an organic compound with the chemical formula C5H7N3. It is a white crystalline solid, soluble in water and organic solvents such as ethanol and dimethylformamide. Its physical properties include a melting point of 178-182 degrees Celsius and a boiling point of 271-273 degrees Celsius.
5-Amino-4-methylpyrimidine has important uses in the pharmaceutical and pesticide industries. It is the building block of nucleotide molecules that can be used to synthesize nucleotide drugs for DNA and RNA. The compound is also an important intermediate for the preparation of a variety of antibiotics, antiviral drugs and anticancer drugs.
The preparation method of 5-Amino-4-methylpyrimidine is usually achieved by the nitration and reduction reaction of pyrimidine. The specific process includes mixing pyrimidine with nitric acid to produce nitropyrimidine, and then reacting nitropyrimidine with a reducing agent (such as sodium bisulfite) to obtain the target product 5-Amino-4-methylpyrimidine.
Regarding safety information, 5-Amino-4-methylpyrimidine is generally safe under normal conditions of use, but appropriate protective measures are still required. It is irritating to the eyes and skin, so wear appropriate personal protective equipment when in contact. Avoid inhaling dust or gas during operation. If ingested or inhaled in large quantities, seek medical help immediately. When storing, it should be kept in a cool, dry place, away from heat and fire.
Last Update:2024-04-09 20:49:11