5-Amino-6-chloro-5-fluoropyrimidine

5-Amino-6-chloro-5-fluoropyrimidine - Names and Identifiers

Name	4-Amino-6-chloro-5-fluoropyrimidine
Synonyms	6-Chloro-5-fluoropyrimidin-4-amine 5-Amino-6-chloro-5-fluoropyrimidine 4-chloro-5-fluoro-6-aminopyrimidine 6-Chloro-5-fluoropyrimidine-4-amine 4-Amino-6-chloro-5-fluoropyrimidine 4-Pyrimidinamine, 6-chloro-5-fluoro-
CAS	851984-15-1

5-Amino-6-chloro-5-fluoropyrimidine - Physico-chemical Properties

Molecular Formula	C4H3ClFN3
Molar Mass	147.54
Density	1.564±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	275.2±35.0℃ (760 Torr)
Flash Point	120.3±25.9℃
pKa	0.27±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

5-Amino-6-chloro-5-fluoropyrimidine - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29335990
Hazard Class	IRRITANT-HARMFUL, AV

5-Amino-6-chloro-5-fluoropyrimidine - Introduction

It is an organic compound with the chemical formula of C4H3ClFN4. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid.
-Solubility: It is almost insoluble in water, but soluble in most organic solvents.
-Melting point: about 211-215 ℃.
-Stability: It is relatively stable at room temperature, but it is combustible and will react when encountering open flames and high temperatures.

Use:
calcium is an important intermediate compound, which has a wide range of applications in the field of drug synthesis and medicine. It can be used to synthesize a range of compounds, such as anti-tumor drugs, drugs that block DNA and RNA synthesis, and other biologically active molecules.

Preparation Method:
-There are many ways to synthesize it. One common synthetic method is by substitution of chlorine and fluorine atoms. The specific steps include reacting pyrimidine with chlorine to obtain 4-amino-6-chloropyrimidine, which is then reacted with a fluorine compound to obtain the target product.

Safety Information:
-is an organic compound, generally has a certain toxicity, should be the correct safety operation.
-During use and storage, keep away from open flames and high temperatures to avoid toxic smoke.
-Wear appropriate protective equipment, including respirators, protective gloves and goggles.
-When in contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-Observe safety regulations during handling and ensure proper disposal of surplus material and waste.

Last Update：2024-04-09 15:18:00