5-BROMO-2-(PIPERAZIN-1-YL)PYRIMIDINE
5-bromo-2-piperazin-1-yl-pyrimidine
CAS: 99931-82-5
Molecular Formula: C8H11BrN4
5-BROMO-2-(PIPERAZIN-1-YL)PYRIMIDINE - Names and Identifiers
5-BROMO-2-(PIPERAZIN-1-YL)PYRIMIDINE - Physico-chemical Properties
| Molecular Formula | C8H11BrN4 |
| Molar Mass | 243.1 |
| Density | 1.516g/cm3 |
| Melting Point | 77 °C |
| Boling Point | 383.436°C at 760 mmHg |
| Flash Point | 185.696°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | Room temperature. |
| Sensitive | Irritant |
| Refractive Index | 1.584 |
| MDL | MFCD01314280 |
5-BROMO-2-(PIPERAZIN-1-YL)PYRIMIDINE - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Note | Irritant |
5-BROMO-2-(PIPERAZIN-1-YL)PYRIMIDINE - Introduction
It is an organic compound with the chemical formula C9H11BrN4, which is a pyrimidine compound with five bromine atoms. The following is a description of the nature, use, preparation and safety information of the substance:
Nature:
-Appearance: Colorless or light yellow crystals.
-Melting point: The melting point of the compound is about 173-175°C.
-Solubility: It has good solubility in common organic solvents.
Use:
As an organic synthesis intermediate, it has a wide range of applications in drug synthesis and research. It can be used to synthesize some drugs, bioactive compounds and pesticides.
Preparation Method:
There are a variety of preparation methods, the following two common:
-Method 1: The target product is synthesized by reacting 2-piperazin-1-yl carboxylic acid with 5-bromopyrimidine under appropriate conditions.
-Method 2: The target product is prepared by substituting 5-bromopyrimidine and piperazine under appropriate solvent and temperature conditions.
Safety Information:
There is relatively limited data on the safety of the process, but general laboratory safety practices should be followed in use and handling. It may irritate the eyes, skin and respiratory system. Wear appropriate personal protective equipment such as safety glasses, laboratory coats, gloves and respiratory protective equipment during handling and contact. During use, care should be taken to avoid inhaling aerosols or touching the skin to avoid ingestion. If you are exposed or unwell, you should seek medical attention immediately.
Nature:
-Appearance: Colorless or light yellow crystals.
-Melting point: The melting point of the compound is about 173-175°C.
-Solubility: It has good solubility in common organic solvents.
Use:
As an organic synthesis intermediate, it has a wide range of applications in drug synthesis and research. It can be used to synthesize some drugs, bioactive compounds and pesticides.
Preparation Method:
There are a variety of preparation methods, the following two common:
-Method 1: The target product is synthesized by reacting 2-piperazin-1-yl carboxylic acid with 5-bromopyrimidine under appropriate conditions.
-Method 2: The target product is prepared by substituting 5-bromopyrimidine and piperazine under appropriate solvent and temperature conditions.
Safety Information:
There is relatively limited data on the safety of the process, but general laboratory safety practices should be followed in use and handling. It may irritate the eyes, skin and respiratory system. Wear appropriate personal protective equipment such as safety glasses, laboratory coats, gloves and respiratory protective equipment during handling and contact. During use, care should be taken to avoid inhaling aerosols or touching the skin to avoid ingestion. If you are exposed or unwell, you should seek medical attention immediately.
Last Update：2024-04-09 21:54:55
