5-BROMO-2-HYDROXY-3-PYRIDINECARBONITRILE

5-BROMO-2-HYDROXY-3-PYRIDINECARBONITRILE - Names and Identifiers

Name	5-bromo-2-oxo-1,2-dihydropyridine-3-carbonitrile
Synonyms	5-bromo-2-hydroxynicotino... 5-Bromo-2-hydroxynicotinonitrile 5-BROMO-2-HYDROXYNICOTINONITRILE 5-Bromo-3-cyano-2(1H)-pyridinone 5-BROMO-3-CAYNO-2(1H)-PYRIDINONE 5-Bromo-3-Cyano-2-Hydroxypyridine 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE 5-bromo-2-hydroxypyridine-3-carbonitrile 5-BROMO-2-HYDROXY-3-PYRIDINECARBONITRILE 3-pyridinecarbonitrile, 5-bromo-2-hydroxy- 5-bromo-2-oxo-1,2-dihydropyridine-3-carbonitrile 5-Bromo-2-oxo-1,2-dihydropyridine-3-carbonitrile 3-pyridinecarbonitrile, 5-bromo-1,2-dihydro-2-oxo-
CAS	405224-22-8
InChI	InChI=1/C6H3BrN2O/c7-5-1-4(2-8)6(10)9-3-5/h1,3H,(H,9,10)

5-BROMO-2-HYDROXY-3-PYRIDINECARBONITRILE - Physico-chemical Properties

Molecular Formula	C6H3BrN2O
Molar Mass	199
Density	1.84±0.1 g/cm3(Predicted)
Melting Point	219-221
Boling Point	292.1±40.0 °C(Predicted)
Flash Point	130.5°C
Vapor Presure	0.00187mmHg at 25°C
pKa	6.87±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.633

5-BROMO-2-HYDROXY-3-PYRIDINECARBONITRILE - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

5-BROMO-2-HYDROXY-3-PYRIDINECARBONITRILE - Introduction

5-bromo-2-oxo-1, is an organic compound with the chemical formula C7H3BrN2O. It is a colorless crystalline solid with special chemical properties and uses.

Nature:
-Appearance: Colorless crystalline solid
-Molecular weight: 212.01g/mol
-melting point: 160-162 ℃
-Boiling point: 416.8 ℃(760 mmHg)

Use:
5-bromo-2-oxo-1, has a wide range of applications in the field of medicine and pesticides.
-Medicine: As a drug intermediate, it can be used to synthesize a variety of biologically active compounds, such as anti-tumor drugs and antiviral drugs.
-Pesticides: can be used in synthetic pesticides, herbicides and fungicides and other agricultural chemicals.

Preparation Method:
5-bromo-2-oxo-1, there are many preparation methods, common methods include the following:
-Pyridine ring addition reaction: react pyridine with bromoacetyl formate, and then perform hydroxylamine treatment to obtain 5-bromo-2-oxo-1.
-Seto-type amino reaction: 2-cyano-5-bromopyridine reacts with ammonia cyanide to obtain 5-bromo-2-oxo-1.

Safety Information:
Regarding 5-bromo-2-oxo-1, there is limited safety and toxicity data, so it is necessary to follow safe operating procedures during use. It can cause potential harm to humans and the environment, including irritation and toxicity. It should be stored in a dry, cool place, avoid contact with oxidants, avoid inhalation, ingestion or contact with skin and eyes. When using this compound, you must wear appropriate protective equipment, such as chemical protective gloves and safety glasses. If inadvertent contact or any discomfort occurs, seek medical attention immediately.

Last Update：2024-04-09 21:54:55