5-BROMO-2-METHOXYBENZOTRIFLUORIDE
4-Bromo-2-(trifluoromethyl)anisole
CAS: 1514-11-0
Molecular Formula: C8H6BrF3O
5-BROMO-2-METHOXYBENZOTRIFLUORIDE - Names and Identifiers
| Name | 4-Bromo-2-(trifluoromethyl)anisole |
| Synonyms | 5-BROMO-2-METHOXYBENZOTRIFLUORIDE 3-Bromo-6-methoxybenzotrifluoride 4-Bromo-2-(trifluotomethyl)anisole 2-(Trifluoromethyl)-4-bromoanisole 4-Bromo-2-(trifluoromethyl)anisole 4-BROMO-2-(TRIFLUOROMETHYL)ANISOLE 4-METHOXY-3-(TRIFLUOROMETHYL)BROMOBENZENE 4-Bromo-1-Methoxy-2-Trifluoromethyl-Benzene 4-bromo-1-methoxy-2-(trifluoromethyl)benzene 1-bromo-4-methoxy-3-(trifluoromethyl)benzene 1-Bromo-4-methoxy-3-(trifluoromethyl)benzene~4-Methoxy-3-(trifluoromethyl)bromobenzene |
| CAS | 1514-11-0 |
| EINECS | 670-639-3 |
| InChI | InChI=1/C8H6BrF3O/c1-13-7-3-2-5(9)4-6(7)8(10,11)12/h2-4H,1H3 |
5-BROMO-2-METHOXYBENZOTRIFLUORIDE - Physico-chemical Properties
| Molecular Formula | C8H6BrF3O |
| Molar Mass | 255.03 |
| Density | 1.563 |
| Boling Point | 120°C 30mm |
| Flash Point | 120°C/30mm |
| Vapor Presure | 0.178mmHg at 25°C |
| BRN | 2525206 |
| Refractive Index | 1.4980 |
5-BROMO-2-METHOXYBENZOTRIFLUORIDE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
5-BROMO-2-METHOXYBENZOTRIFLUORIDE - Introduction
4-Bromo-2-(trifluoromethyl)anisole is an organic compound with the chemical formula C8H6BrF3O. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless liquid or solid
-Boiling point: 220-223 ℃
-Density: 1.669g/cm³
-Melting point: 24-25 ℃
-Soluble in organic solvents such as ethanol, acetone and ethyl acetate
Use:
4-Bromo-2-(trifluoromethyl)anisole is commonly used as a reagent and intermediate in organic synthesis, and is widely used in the manufacturing process of pesticides and drugs. It can also be used as a solvent in the formulation of coatings, paints and adhesives.
Method:
4-Bromo-2-(trifluoromethyl)anisole can be synthesized by the following steps:
1.2-(trifluoromethyl) benzyl alcohol reacts with carbon tetrabromide (CBr4) to generate 2-bromo-(trifluoromethyl) benzyl alcohol.
2. 2-bromo-(trifluoromethyl) benzyl alcohol reacts with sodium carbonate (Na2CO3) and copper bromide (CuBr2) under alkaline conditions to generate 4-Bromo-2-(trifluoromethyl)anisole.
Safety Information:
-The compound is irritating, avoid contact with skin and eyes.
-Pay attention to protective measures during use, such as wearing safety gloves and glasses.
-Avoid inhaling the vapor or gas of the compound, and make sure to use it in a well-ventilated place.
-Observe relevant safety regulations and standard procedures during storage and handling.
Please note that the use and handling of chemicals involve certain risks, so when using or handling this compound, you should follow appropriate laboratory practices and take necessary safety measures.
Nature:
-Appearance: Colorless liquid or solid
-Boiling point: 220-223 ℃
-Density: 1.669g/cm³
-Melting point: 24-25 ℃
-Soluble in organic solvents such as ethanol, acetone and ethyl acetate
Use:
4-Bromo-2-(trifluoromethyl)anisole is commonly used as a reagent and intermediate in organic synthesis, and is widely used in the manufacturing process of pesticides and drugs. It can also be used as a solvent in the formulation of coatings, paints and adhesives.
Method:
4-Bromo-2-(trifluoromethyl)anisole can be synthesized by the following steps:
1.2-(trifluoromethyl) benzyl alcohol reacts with carbon tetrabromide (CBr4) to generate 2-bromo-(trifluoromethyl) benzyl alcohol.
2. 2-bromo-(trifluoromethyl) benzyl alcohol reacts with sodium carbonate (Na2CO3) and copper bromide (CuBr2) under alkaline conditions to generate 4-Bromo-2-(trifluoromethyl)anisole.
Safety Information:
-The compound is irritating, avoid contact with skin and eyes.
-Pay attention to protective measures during use, such as wearing safety gloves and glasses.
-Avoid inhaling the vapor or gas of the compound, and make sure to use it in a well-ventilated place.
-Observe relevant safety regulations and standard procedures during storage and handling.
Please note that the use and handling of chemicals involve certain risks, so when using or handling this compound, you should follow appropriate laboratory practices and take necessary safety measures.
Last Update：2024-04-09 15:17:52
